TY - JOUR A1 - Gough, A A1 - Vernetti, L A1 - Bergenthal, L A1 - Shun, T Y A1 - Taylor, D L T1 - The MicroPhysiology Systems Database for analyzing and modeling compound interactions with human and animal organ models. Y1 - 2016/06/1 N1 - R835736 N1 - R835736C004 VL - 2 IS - 2 SP - 103 EP - 117 ER - TY - JOUR A1 - Lee-Montiel, F T A1 - George, S M A1 - Gough, A H A1 - Sharma, A D A1 - Wu, J A1 - DeBiasio, R A1 - Vernetti, L A A1 - Taylor, D L T1 - “Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems”, Exp Biol Med (Maywood). Y1 - 2017/10/ N1 - R835736C004 VL - 242 IS - 16 SP - 1617 EP - 1632 ER - TY - JOUR A1 - Li, X A1 - George, S M A1 - Vernetti, L A1 - Gough, A H A1 - Taylor, D L T1 - A glass-based, continuously zonated and vascularized human liver acinus microphysiological system (vLAMPS) designed for experimental modeling of diseases and ADME/TOX Y1 - 2018/09/ N1 - R835736C004 JF - LAB ON A CHIP J1 - LAB ON A CHIP VL - 18 IS - 17 SP - 2614 EP - 2631 ER - TY - JOUR A1 - Senutovitch, N A1 - Vernetti, L A1 - Boltz, R A1 - DeBiasio, R A1 - Gough, A A1 - Taylor, D L T1 - Fluorescent protein biosensors applied to microphysiological systems. Y1 - 2015/06/ N1 - R835736 N1 - R835736C004 JF - EXPERIMENTAL BIOLOGY AND MEDICINE J1 - EXP BIOL MED VL - 240 IS - 6 SP - 795 EP - 808 ER - TY - JOUR A1 - Soto-Gutierrez, A A1 - Gough, A A1 - Vernetti, L A A1 - Taylor, D L A1 - Monga, S P T1 - Pre-clinical and clinical investigations of metabolic zonation in liver diseases: the potential of microphysiology systems. Y1 - 2017/10/ N1 - R835736 N1 - R835736C004 JF - EXPERIMENTAL BIOLOGY AND MEDICINE J1 - EXP BIOL MED VL - 242 IS - 16 SP - 1605 EP - 1616 ER - TY - JOUR A1 - Vernetti, L A A1 - Senutovitch, N A1 - Boltz, R A1 - DeBiasio, R A1 - Shun, T Y A1 - Gough, A A1 - Taylor, D L T1 - A human liver microphysiology platform for investigating physiology, drug safety, and disease models. Y1 - 2016/01/ N1 - R835736 N1 - R835736C004 JF - EXPERIMENTAL BIOLOGY AND MEDICINE J1 - EXP BIOL MED VL - 241 IS - 1 SP - 101 EP - 114 ER - TY - JOUR A1 - Vernetti, L A A1 - Gough, A A1 - Baetz, N A1 - Blutt, S A1 - Broughman, J R A1 - Brown JA, A1 - Foulke-Abel, J A1 - Hasan, N A1 - In, J A1 - Kelly, E A1 - Kovbasnjuk, O A1 - Repper J, A1 - Senutovitch, N A1 - Stabb, J A1 - Yeung, C A1 - Zachos, N C A1 - Donowitz, M A1 - Estes M, A1 - Himmelfarb, J A1 - Truskey, G A1 - Wikswo, J P A1 - Taylor, D T1 - Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Y1 - 2017/02/8 N1 - R835736 N1 - R835738C005 N1 - R835736C004 N1 - R835738C002 VL - 7 SP - 42296 (14 pp.) ER - TY - JOUR A1 - Vernetti, L A A1 - Vogt, A A1 - Gough, A A1 - Taylor, D L T1 - Evolution of experimental models of the liver to predict human drug hepatotoxicity and efficacy. Y1 - 2017/02/ N1 - R835736 N1 - R835736C004 VL - 21 IS - 1 SP - 197 EP - 214 ER - TY - JOUR A1 - Vernetti, L A1 - Gough, A A1 - Baetz, N A1 - Blutt, S A1 - Broughman, J R A1 - Brown, J A A1 - Foulke-Abel, J A1 - Hasan, N A1 - In, J A1 - Kelly, E A1 - Kovbasnjuk, O A1 - Repper, J A1 - Senutovitch, N A1 - Stabb, J A1 - Yeung, C A1 - Zachos, N C A1 - Donowitz, M A1 - Himmelfarb, J A1 - Truskey, G A1 - Wikswo, J P A1 - Taylor, D L T1 - Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Y1 - 2017/02/8 N1 - R835738 N1 - R835738C002 N1 - R835736C004 VL - 7 SP - 42296 (14 pp.) ER - TY - JOUR A1 - Vernetti, L A1 - Gough, A A1 - Baetz, N A1 - Blutt, S A1 - Broughman, J R A1 - Brown, J A A1 - Foulke-Abel, J A1 - Hasan, N A1 - In, J A1 - Kelly, E A1 - Kovbasnjuk, O A1 - Repper, J A1 - Senutovitch, N A1 - Stabb, J A1 - Yeung, C A1 - Zachos, N C A1 - Donowitz, M A1 - Estes, M A1 - Himmelfarb, J A1 - Truskey, G A1 - Wikswo, J P A1 - Taylor, D L T1 - Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle. Y1 - 2017/02/8 N1 - R835738 N1 - R835736 N1 - R835736C005 N1 - R835738C005 N1 - R835736C004 N1 - R835738C003 JF - SCIENTIFIC REPORTS J1 - Scientific Reports VL - 7 SP - 42296 (15 pp.) ER - TY - CONF A1 - Taylor, D L T1 - Evolution of a human liver MPS platform. Y1 - 2017/04/24 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - Spatial tumor biology for phenotyping, immunotyping and recapitulating tumor microenvironments. Y1 - 2017/08/ N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L A1 - Vernetti, L A T1 - Functional application of liver organotypic culture models. Y1 - 2017/02/22 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - Role of human liver microphysiology systems as part of a quantitative systems pharmacology platform for investigating ADMET and liver disease progression. Y1 - 2017/07/24 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - The evolution, challenges and recent application of high content screening. Y1 - 2017/06/9 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - The next technology wave: biosensors, extreme computing, and organ chips for predicting cardiovascular toxicity. Y1 - 2017/03/12-16 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - Quantitative systems pharmacology of liver diseases: human liver microphysiology system (MPS). Y1 - 2017/03/23 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - Evolution of a human liver microphysiology system. Y1 - 2017/05/5 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - The application of quantitative systems pharmacology to investigate liver diseases and toxicology. Y1 - 2017/05/8 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - Investigating human liver disease progression with 3D microfluidic models. Y1 - 2017/11/6 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - [title not provided]. Y1 - 2017/10/5 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L A1 - Gough, A T1 - A human liver-on-a-chip as a key experimental component of the application of quantitative systems pharmacology. Y1 - 2017/10/6 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - Quantitative systems pharmacology (QSP) in drug discovery. Y1 - 2017/09/18 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - Metastatic breast cancer explored in a human, 3D, microfluidic liver chip. Y1 - 2017/09/26 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - Role of human liver microphysiology systems as part of a quantitative systems pharmacology platform for investigating ADMET and liver disease progression. Y1 - 2017/09/5 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - A Human Liver Microphysiology System for Drug Discovery and development N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - Application of quantitative systems pharmacology (QSP) and human microphysiology systems (MPS) to develop therapeutic strategies for liver disease N1 - R835736C004 ER - TY - CONF A1 - Taylor, D L T1 - Human Microphysiology Systems as a Critical Component of Quantitative Systems Pharmacology Applied to Drug Discovery and Development N1 - R835736C004 ER - TY - CONF A1 - Taylor, A1 - DL, T1 - The Evolution of Human Experimental Models for Drug Discovery/Development and Precision medicine:Different Model Types, Reproducibility, Applications and Future Impact N1 - R835736C004 ER - TY - CONF A1 - Vernetti, L A T1 - Development of an integrated liver microphysiological system. Y1 - 2015/10/18-22 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Vernetti, L A T1 - Predicting human toxicity from MOA based high content imaging in 2D and 3D microphysiology systems. Y1 - 2016/10/13 N1 - R835736 N1 - R835736C004 ER - TY - CONF A1 - Vernetti, L A A1 - Gough, A A1 - Bergenthal, L A1 - Karcher, S A1 - Shun, T A1 - Wolter, Q A1 - Gavlock D, A1 - Reese, C A1 - Schurdak, M A1 - Taylor, D L T1 - The Human Liver Acinus MicroPhysiology System (LAMPS) for Analyzing and Ranking the Hepatotoxicity Potential of Compounds and as a Metabolic Component for Integration with other OCM N1 - R835736C004 ER - TY - CONF A1 - Vernetti, L T1 - Application and challenges to constructing a competent human liver on a chip. Y1 - 2016/03/17 N1 - R835736 N1 - R835736C004 ER - TY - CONF T1 - June 10th-15, 2018. N1 - R835736C004 ER -