TY  - JOUR
A1  - Chen, H 
A1  - Streifel, K M
A1  - Singh, V 
A1  - Yang, D 
A1  - Mangini, L 
A1  - Wulff, H 
A1  - Lein, P J
T1  - From the cover: BDE-47 and BDE-49 inhibit axonal growth in primary rat hippocampal neuron-glia co-cultures via ryanodine receptor-dependent mechanisms.
Y1  - 2017/04/1
N1  - R835550
JF  - TOXICOLOGICAL SCIENCES
J1  - TOXICOL SCI
J2  - Toxicol.Sci.
J3  - Toxicological Sciences
VL  - 156
IS  - 2
SP  - 375
EP  - 386
ER  - 


TY  - JOUR
A1  - Dach, K 
A1  - Bendt, F 
A1  - Huebenthal, U 
A1  - Giersiefer, S 
A1  - Lein, P J
A1  - Heuer, H 
A1  - Fritschea, E 
T1  - BDE-99 impairs differentiation of human and mouse NPCs into the oligodendroglial lineage by species-specific modes of action.
Y1  - 2017/03/20
N1  - R835550
JF  - SCIENTIFIC REPORTS
J1  - Scientific Reports
VL  - 7
SP  - 44861 (11 pp.)
ER  - 


TY  - JOUR
A1  - Frank, D F
A1  - Miller, G W
A1  - Harvey, D J
A1  - Brander, S M
A1  - Geist, J 
A1  - Connon, R E
A1  - Lein, P J
T1  - Bifenthrin causes transcriptomic alterations in mTOR and ryanodine receptor-dependent signaling and delayed hyperactivity in developing zebrafish (<em>Danio rerio</em>).
Y1  - 2018/07/01
N1  - R835799
N1  - R835550
VL  - 200
SP  - 50
EP  - 61
ER  - 


TY  - JOUR
A1  - Harrill, J A
A1  - Chen, H 
A1  - Streifel, K M
A1  - Yang, D 
A1  - Mundy, W R
A1  - Lein, P J
T1  - Ontogeny of biochemical, morphological and functional parameters of synaptogenesis in primary cultures of rat hippocampal and cortical neurons.
Y1  - 2015/02/15
N1  - R835432
N1  - R835550
JF  - MOLECULAR BRAIN
VL  - 8
SP  - 10 (15 pp.)
ER  - 


TY  - JOUR
A1  - Klose, J 
A1  - TRigges, J 
A1  - Masjosthusmann, S 
A1  - Schmuck, K 
A1  - Bendt, F 
A1  - Hubenthal, U 
A1  - Petzsch, P 
A1  - Kohrer, K 
A1  - Koch, K 
A1  - Fritsche, E 
T1  - TBBPA Targets Converging Key Events of Human Oligodendrocyte Development Resulting in Two Novel AOPs
Y1  - 2021//23
N1  - R835550
JF  - ALTEX
VL  - 38
IS  - 2
SP  - 215
EP  - 234
ER  - 


TY  - JOUR
A1  - Singh, L 
A1  - Pressly, B 
A1  - Mengeling, B J
A1  - Fettinger, J C
A1  - Furlow, J D
A1  - Lein, P J
A1  - Wulff, H 
A1  - Singh, V 
T1  - Chasing the elusive benzofuran impurity of the THR antagonist NH-3: synthesis, isotope labeling, and biological activity.
Y1  - 2016/03/4
N1  - R835164
N1  - R835550
JF  - JOURNAL OF ORGANIC CHEMISTRY
J1  - J ORG CHEM
VL  - 81
IS  - 5
SP  - 1870
EP  - 1876
ER  - 


TY  - JOUR
T1  - Transcriptomic profiling of mTOR and ryanodine receptor signaling molecules in developing zebrafish in the absence and presence of PCB 95.
Y1  - 2017/11/29
N1  - R835550
VL  - 5
IS  - e4106
SP  - e4106. doi
ER  - 


TY  - JOUR
T1  - A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling.
Y1  - 2017/09/
N1  - R835550
VL  - 190
SP  - 1
EP  - 10
ER  - 


TY  - CONF
A1  - Dach, K 
A1  - Giersiefer, S 
A1  - Heuer, H 
A1  - Fritsche, E 
T1  - Neurospheres as a 3D <em>in vitro</em> model for DNT testing: studying endocrine disruption of thyroid hormone signaling during brain development in a species-specific context.
Y1  - 2015/02/23-24
N1  - R835550
ER  - 


TY  - CONF
A1  - Dach, K 
A1  - Giersiefer, S 
A1  - Bendt, F 
A1  - Huebenthal, U 
A1  - Heuer, H 
A1  - Fritsche, E 
T1  - Characterization of molecular and cellular effects of thyroid hormone within an AOP frame for thyroid hormone disruption using human and murine neural progenitor cells.
Y1  - 2015/09/20-23
N1  - R835550
ER  - 


TY  - CONF
A1  - Giersiefer, S 
T1  - Species-specific effects of thyroid hormone on neurodevelopmental processes <em>in vitro</em>.
Y1  - 2014/12/4-5
N1  - R835550
ER  - 


TY  - CONF
A1  - Giersiefer, S 
T1  - Distinct actions of thyroid hormone on early neurodevelopmental processes of human and rodent NPCs <em>in vitro</em>.
Y1  - 2014/12/5-7
N1  - R835550
ER  - 


TY  - CONF
A1  - Giersiefer, S 
A1  - Dach, K 
A1  - Heuer, H 
A1  - Fritsche, E 
T1  - Identification of AOPs involving disruption of thyroid hormone signaling in neurodevelopmental processes by using 3D neurospheres.
Y1  - 2015/03/22-26
N1  - R835550
ER  - 


TY  - CONF
A1  - Giersiefer, S 
T1  - Generation of the molecular basis for studying thyroid hormone disruption in neural progenitor cells of humans and rats.
Y1  - 2015/09/20-23
N1  - R835550
ER  - 


TY  - CONF
A1  - Hayakawa, K A
A1  - Walter, K M
A1  - Miller, G W
A1  - Lein, P J
T1  - Gene expression of thyroid hormone signaling pathways during neurodevelopment.
Y1  - 2015/03/22-26
N1  - R835550
ER  - 


TY  - CONF
A1  - Lein, P J
T1  - Identification of molecular, cellular and behavioral endpoints associated with developmental hyperthyroidism and hypothyroidism in larval zebrafish.
Y1  - 2016/03/13-17
N1  - R835550
ER  - 


TY  - CONF
A1  - Lein, P J
T1  - Neurodevelopmental endpoints modulated by thyroid hormone in primary rat neuron-glia co-cultures.
Y1  - 2016/03/13-17
N1  - R835550
ER  - 


TY  - CONF
A1  - Lein, P J
T1  - Developmental hyperthyroidism and hypothyroidism in larval zebrafish alter oligodendrocyte precursor cell proliferation and maturation.
Y1  - 2016/11/
N1  - R835550
ER  - 


TY  - CONF
A1  - Lein, P 
T1  - Thyroid hormone drives early neurodevelopmental processes of humans and rodents in vitro (Fritsche lab).
Y1  - 2014/08/
N1  - R835550
ER  - 


TY  - CONF
A1  - Lein, P 
T1  - BDE-47 and BDE-49 selectively disrupt axonal outgrowth in cultured hippocampal neurons (Lein lab).
Y1  - 2014/03/23-27
N1  - R835550
ER  - 


TY  - CONF
A1  - Lein, P 
T1  - Of mice and men: mechanistic studies on the developmental neurotoxicity of polybrominated diphenyl ethers (PBDEs) in a 3D in vitro model (Frische lab).
Y1  - 2014/09/
N1  - R835550
ER  - 


TY  - CONF
A1  - Walter, K M
A1  - Miller, G W
A1  - Chang, Y 
A1  - Hayakawa, K A
A1  - Draper, B W
A1  - Lein, P 
T1  - Development of a zebrafish model to identify adverse outcome pathways linking thyroid hormone disruption to developmental neurotoxicity.
Y1  - 2015/03/22-26
N1  - R835550
ER  -