Grantee Research Project Results
Publications Details for Grant Number R824790
Cellular Mechanisms of Pulmonary Inflammation by Environmental Particles
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| Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
|---|---|---|---|---|---|---|
| Conference Proceedings | Air particulate effects on inflammation-primed targets: in vitro and in vivo analysis. | None | Ning Y, Imrich A, Goldsmith C, Hamada K, Kobzik L | Ning Y, Imrich A, Goldsmith C, Hamada K, Kobzik L. Air particulate effects on inflammation-primed targets:in vitro and in vivo analysis. In:Measurement of Toxic and Related Air Pollutants:Proceedings of a Specialty Conference, September 1-3, 1998, Cary, NC. Volume I, U.S. Environmental Protection Agency, EPA 600-R-98-203, 2000, pp. 73-84. |
R824790 (Final) |
not available |
| Journal Article | Alveolar macrophage interaction with air pollution particulates. | ENVIRONMENTAL HEALTH PERSPECTIVES | Goldsmith CA, Frevert C, Imrich A, Sioutas C, Kobzik L | Goldsmith CA, Frevert C, Imrich A, Sioutas C, Kobzik L. Alveolar macrophage interaction with air pollution particulates. Environmental Health Perspectives 1997;105(Suppl 5):1191-1195. |
R824790 (Final) |
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| Journal Article | Analysis of air pollution particulate-mediated oxidant stress in alveolar macrophages. | JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A | Goldsmith CA, Imrich A, Danaee H, Ning Y, Kobzik L | Goldsmith CA, Imrich A, Danaee H, Ning Y, Kobzik L. Analysis of air pollution particulate-mediated oxidant stress in alveolar macrophages. Journal of Toxicology and Environmental Health-Part A 1998;54(7):529-545. |
R824790 (Final) |
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| Journal Article | Effects of environmental aerosols on airway hyperresponsiveness in a murine model of asthma. | INHALATION TOXICOLOGY | Goldsmith CA, Hamada K, Ning YY, Qin GZ, Catalano P, Murthy GGK, Lawrence J, Kobzik L | Goldsmith CA, Hamada K, Ning YY, Qin GZ, Catalano P, Murthy GGK, Lawrence J, Kobzik L. Effects of environmental aerosols on airway hyperresponsiveness in a murine model of asthma. Inhalation Toxicology 1999;11(11):981-998. |
R824790 (Final) |
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| Journal Article | Combined air pollution particle and ozone exposure increases airway responsiveness in mice. | INHALATION TOXICOLOGY | Goldsmith C-AW, Ning YY, Qin G, Imrich A, Lawrence J, Murthy GGK, Catalano PJ, Kobzik L | Goldsmith C-AW, Ning YY, Qin G, Imrich A, Lawrence J, Murthy GGK, Catalano PJ, Kobzik L. Combined air pollution particle and ozone exposure increases airway responsiveness in mice. Inhalation Toxicology 2002;14(4):325-347. |
R824790 (Final) R826779 (Final) |
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| Journal Article | Intracellular oxidant production and cytokine responses in lung macrophages: evaluation of fluorescent probes. | JOURNAL OF LEUKOCYTE BIOLOGY | Imrich A, Ning YY, Kobzik L | Imrich A, Ning YY, Kobzik L. Intracellular oxidant production and cytokine responses in lung macrophages: evaluation of fluorescent probes. Journal of Leukocyte Biology 1999;65(4):499-507. |
R824790 (Final) |
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| Journal Article | Lipopolysaccharide priming amplifies lung macrophage tumor necrosis factor production in response to air particles. | TOXICOLOGY AND APPLIED PHARMACOLOGY | Imrich A, Ning YY, Koziel H, Coull B, Kobzik L | Imrich A, Ning YY, Koziel H, Coull B, Kobzik L. Lipopolysaccharide priming amplifies lung macrophage tumor necrosis factor production in response to air particles. Toxicology and Applied Pharmacology 1999;159(2):117-124. |
R824790 (Final) |
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| Journal Article | Alveolar macrophage cytokine production in response to air particles in vitro: role of endotoxin. | JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A | Ning YY, Imrich A, Goldsmith CA, Qin GZ, Kobzik L | Ning YY, Imrich A, Goldsmith CA, Qin GZ, Kobzik L. Alveolar macrophage cytokine production in response to air particles in vitro: role of endotoxin. Journal of Toxicology and Environmental Health-Part A 2000;59(3):165-180. |
R824790 (Final) |
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| Journal Article | Lung epithelial cell (A549) interaction with unopsonized environmental particulates: Quantitation of particle-specific binding and IL-8 production. | EXPERIMENTAL LUNG RESEARCH | Stringer B, Imrich A, Kobzik L | Stringer B, Imrich A, Kobzik L. Lung epithelial cell (A549) interaction with unopsonized environmental particulates: Quantitation of particle-specific binding and IL-8 production. Experimental Lung Research 1996;22(5):495-508. |
R824790 (Final) |
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| Journal Article | Environmental particulate-mediated cytokine production in lung epithelial cells (A549): role of preexisting inflammation and oxidant stress. | JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A | Stringer B, Kobzik L | Stringer B, Kobzik L. Environmental particulate-mediated cytokine production in lung epithelial cells (A549): role of preexisting inflammation and oxidant stress. Journal of Toxicology and Environmental Health-Part A 1998;55(1):31-44. |
R824790 (Final) |
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.