Grantee Research Project Results
Publications Details for Grant Number CR830686
Species-Specific Xenobiotic Metabolism Mediated by the Steroid and Xenobiotic Receptor SXR
Other Views
- All
Publications - Selected
Publication Types - Journal
Articles - Publications Submitted
After Final Report - Redisplay this page without
Reference Title, Journal, and Author Columns - Display this Page
in RIS Format
| Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
|---|---|---|---|---|---|---|
| Journal Article | Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates. | MOLECULAR ENDOCRINOLOGY | Grun F, Watanabe H, Zamanian Z, Maeda L, Arima K, Cubacha R, Gardiner DM, Kanno J, Iguchi T, Blumberg B | Grun F, Watanabe H, Zamanian Z, Maeda L, Arima K, Cubacha R, Gardiner DM, Kanno J, Iguchi T, Blumberg B. Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates. Molecular Endocrinology 2006;20(9):2141-2155. |
CR830686 (2006) |
|
| Journal Article | Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling. | ENDOCRINOLOGY | Grun F, Blumberg B | Grun F, Blumberg B. Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling. Endocrinology 2006;147(6):S50-S55. |
CR830686 (2006) |
|
| Journal Article | Up-regulation of the alligator CYP3A77 gene by toxaphene and dexamethasone and its short term effect on plasma testosterone concentrations. | AQUATIC TOXICOLOGY | Gunderson MP, Kohno S, Blumberg B, Iguchi T, Guillette Jr LJ | Gunderson MP, Kohno S, Blumberg B, Iguchi T, Guillette Jr LJ. Up-regulation of the alligator CYP3A77 gene by toxaphene and dexamethasone and its short term effect on plasma testosterone concentrations. Aquatic Toxicology 2006;78(3):272-283. |
CR830686 (2006) |
|
| Journal Article | Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR). | ENVIRONMENTAL HEALTH PERSPECTIVES | Tabb MM, Kholodovych V, Grün F, Zhou C, Welsh WJ, Blumberg B | Tabb MM, Kholodovych V, Grün F, Zhou C, Welsh WJ, Blumberg B. Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR). Environmental Health Perspectives 2004;112(2):163-169. |
CR830686 (2003) CR830686 (2006) R826133 (Final) |
not available |
| Journal Article | New modes of action for endocrine-disrupting chemicals. | MOLECULAR ENDOCRINOLOGY | Tabb MM, Blumberg B | Tabb MM, Blumberg B. New modes of action for endocrine-disrupting chemicals. Molecular Endocrinology 2006;20(3):475-482. |
CR830686 (2006) |
|
| Journal Article | Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. | DRUG METABOLISM AND DISPOSITION | Zhou C, Tabb MM, Sadatrafiei A, Grün F, Blumberg B | Zhou C, Tabb MM, Sadatrafiei A, Grün F, Blumberg B. Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. Drug Metabolism and Disposition 2004;32(10):1075-1082. |
CR830686 (2004) CR830686 (2006) |
not available |
| Journal Article | Mutual repression between steroid and xenobiotic receptor and NF-κB signaling pathways links xenobiotic metabolism and inflammation. | THE JOURNAL OF CLINICAL INVESTIGATION | Zhou C, Tabb MM, Nelson EL, Grun F, Verma S, Sadatrafiei A, Lin M, Mallick S, Forman BM, Thummel KE, Blumberg B | Zhou C, Tabb MM, Nelson EL, Grun F, Verma S, Sadatrafiei A, Lin M, Mallick S, Forman BM, Thummel KE, Blumberg B. Mutual repression between steroid and xenobiotic receptor and NF-κB signaling pathways links xenobiotic metabolism and inflammation. The Journal of Clinical Investigation 2006b;116(8):2280-2289. |
CR830686 (2006) |
|
| Journal Article | Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. | THE JOURNAL OF CLINICAL INVESTIGATION | Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, Thummel KE | Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, Thummel KE. Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. The Journal of Clinical Investigation 2006a;116(6):1703-1712. |
CR830686 (2006) |
|
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the National Institute of Health Sciences, Tokyo, Japan, January 2003. |
CR830686 (2003) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the Saitama University Medical School, Saitama, Japan, October 2003. |
CR830686 (2003) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the Academy of Lifelong Learning, Irvine, CA, February 2003. |
CR830686 (2003) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the National Institute of Health Sciences, Tokyo, Japan, October 2003. |
CR830686 (2003) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the National Institute for Basic Biology Ecotoxicogenomics Symposium, Okazaki, Japan, October 2003. |
CR830686 (2003) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the National Institute for Basic Biology, Okazaki, Japan, January 2003. |
CR830686 (2003) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the Symposium on the Environmental Risks of Endocrine Disruptors, Matsuyama, Japan, January 2003. |
CR830686 (2003) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the Toxicogenomics International Forum 2003, Tokyo, Japan, October 9-10, 2003. |
CR830686 (2003) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the National Institute of Health Sciences Meeting on Progress in Endocrine Disruptor Research, Tokyo, Japan, January 2003. |
CR830686 (2003) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the Eisai Summer Symposium in Molecular Biology, Tokyo, Japan, August 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the Department of Stem Cell Research, Pochon Cha Medical School, Seoul, Korea, August 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the Department of Environmental and Community Medicine, University of California at Irvine, Irvine, CA, January 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the U.S. Delegate, Organization for Economic Co-operation and Development/International Programme on Chemical Safety Workshop on Toxicogenomics, Kyoto, Japan, October 13-15, 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the Toxicogenomics International Forum 2004, Kyoto, Japan, October 12-13, 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the 7th International Symposium on Environmental Endocrine Disrupters, Nagoya, Japan, December 15-17, 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry of New Jersey, Piscataway, NJ, September 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the Department of Life Sciences and Biology, University of Tokyo, (Komaba Campus), Tokyo, Japan, December 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the International Symposium on Steroid Hormone Receptor Superfamily and Molecular Signaling, Thiruvanathapuram, Kerala, India, November 25-27, 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the Department of Molecular Biology and Biochemistry, University of California at Irvine, Irvine, CA, September 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the Department of Neuroendocrinology, University of Texas at Austin, Austin, TX, December 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the National Institute of Health Sciences, Tokyo, Japan, August 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the Department of Zoological Sciences, University of Tokyo, (Hongo Campus), Tokyo, Japan, December 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the Human Health Symposium—A Science to Achieve Results Progress Review Workshop, Philadelphia, PA, October 28-29, 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the Division of Toxicology, University of Texas at Austin, Austin, TX, December 2004. |
CR830686 (2004) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the International Workshop on the Latest Concepts in Developmental Biology, Los Cocos, Cordoba, Argentina, April 2006 (invited speaker). |
CR830686 (2006) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the Johns Hopkins University, Genetics and Public Policy Center's Genetics Perspectives on Policy Seminar (GenePOPS), Washington, DC, December 2006 (invited panelist). |
CR830686 (2006) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the Omix Informatics Symposium, Tokyo, Japan, March 2006 (invited speaker). |
CR830686 (2006) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the Special Course in Omics-Based Medicine, Tokyo Medical and Dental University, Tokyo, Japan, March 2006 (invited lecturer). |
CR830686 (2006) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented to the Boston University Department of Biology, Boston, MA, November 2006 (invited speaker). |
CR830686 (2006) |
not available |
| Presentation | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. Presented at the City of Hope MoLAR biannual meeting, Duarte, CA, October 2006 (invited speaker). |
CR830686 (2006) |
not available |
| Proceedings | Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. | None | Blumberg B | Blumberg B. Species-specific xenobiotic metabolism mediated by the steroid and xenobiotic receptor SXR. In: Proceedings of the Human Health Symposium—A Science to Achieve Results Progress Review Workshop, Philadelphia, PA, October 28-29, 2004, pp.35-36. |
CR830686 (2004) |
not available |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.