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Grantee Research Project Results

Publications Details for Grant Number R826782

Airborne Particulate Matter-Induced Lung Inflammation

RFA: Health Effects of Particulate Matter and Associated Air Pollutants (1998)

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Journal Article (5)
Presentation (3)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Journal Article Airway responsiveness after acute exposure to urban particulate matter 1648 in a DO11. AJP LUNG CELLULAR AND MOLECULAR PHYSIOLOGY Archer AJ, Cramton JLH, Pfau JC, Colasurdo G, Holian A Archer AJ, Cramton JLH, Pfau JC, Colasurdo G, Holian A. Airway responsiveness after acute exposure to urban particulate matter 1648 in a DO11.10 murine model. AJP Lung Cellular and Molecular Physiology 2004;286(2):L337-L343. R826782 (Final)
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Journal Article Silica and PM1648 modify human alveolar macrophage antigen-presenting cell activity in vitro. JOURNAL OF ENVIRONMENTAL PATHOLOGY, TOXICOLOGY AND ONCOLOGY Hamilton RF, Marshall GD, Holian A Hamilton RF, Marshall GD, Holian A. Silica and PM1648 modify human alveolar macrophage antigen-presenting cell activity in vitro. Journal of Environmental Pathology, Toxicology and Oncology 2001;20(Suppl 1):75-84. R826782 (Final)
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Journal Article A comparison of asbestos and urban particulate matter in the in vitro modification of human alveolar macrophage antigen-presenting cell function. EXPERIMENTAL LUNG RESEARCH Hamilton RF, Holian A, Morandi MT Hamilton Jr. RF, Holian A, Morandi MT. A comparison of asbestos and urban particulate matter in the in vitro modification of human alveolar macrophage antigen-presenting cell function. Experimental Lung Research 2004;30(2):147-162. R826782 (Final)
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Journal Article Surface components of airborne particulate matter induce macrophage apoptosis through scavenger receptors. TOXICOLOGY AND APPLIED PHARMACOLOGY Obot CJ, Morandi MT, Beebe TP, Hamilton RF, Holian A Obot CJ, Morandi MT, Beebe TP, Hamilton RF, Holian A. Surface components of airborne particulate matter induce macrophage apoptosis through scavenger receptors. Toxicology and Applied Pharmacology 2002;184(2):98-106. R826782 (Final)
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Journal Article A comparison of murine and human alveolar macrophage responses to urban particulate matter. INHALATION TOXICOLOGY Obot CJ, Morandi MT, Hamilton RF, Holian A Obot CJ, Morandi MT, Hamilton RF, Holian A. A comparison of murine and human alveolar macrophage responses to urban particulate matter. Inhalation Toxicology 2004;16(2):69-76. R826782 (Final)
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Presentation Alveolar macrophages from Balb/C mice as a model for exploring the mechanism of particulate matter toxicity. None Obot CJ, Morandi MT, Hamilton RF, Holian A Obot CJ, Morandi MT, Hamilton RF, Holian A. Alveolar macrophages from Balb/C mice as a model for exploring the mechanism of particulate matter toxicity. Presented at the 41st Annual Meeting of the Society of Toxicology, Nashville, TN, March 17-21, 2002. R826782 (Final)
not available
Presentation Both organic and metallic fractions of particulate matter induce apoptosis by interacting with scavenger receptors. None Obot CJ, Holian A, Morandi MT, Hamilton R, Wilson B, Felder T, Beebe TP Obot CJ, Holian A, Morandi MT, Hamilton R, Wilson B, Felder T, Beebe TP. Both organic and metallic fractions of particulate matter induce apoptosis by interacting with scavenger receptors. Presented at the Annual Meeting of the Texas Gulf Coast Society of Toxicology, Austin, TX, October 26-27, 2000. R826782 (Final)
not available
Presentation Removal of acid- and organic solvent-extractable chemicals influences the toxicity of fine particulate matter. None Obot CJ, Holian A, Morandi MT, Felder TB Obot CJ, Holian A, Morandi MT, Felder TB. Removal of acid- and organic solvent-extractable chemicals influences the toxicity of fine particulate matter. Presented at the Annual Gulf Coast Society of Toxicology Meeting, Houston, TX, November 19-20, 1999. R826782 (Final)
not available

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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