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Grantee Research Project Results

Journal Publications Details for Grant Number R832417C003

Biological Assessment of the Toxicity of PM and PM Components

RFA: Particulate Matter Research Centers (2004)

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Journal Article (4)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Journal Article Murine lung responses to ambient particulate matter: genomic analysis and influence on airway hyperresponsiveness. None Wang T, Moreno-Vinasco L, Huang Y, Lang GD, Linares JD, Goonewarena SN, Grabavoy A, Samet JM, Geyh AS, Breysse PN, Lussier YA, Natarajan V, Garcia JGN Wang T, Moreno-Vinasco L, Huang Y, Lang GD, Linares JD, Goonewardena SN, Grabavoy A, Samet JM, Geyh AS, Breysse PN, Lussier YA, Natarajan V, Garcia JGN. Murine lung responses to ambient particulate matter: genomic analysis and influence on airway hyperresponsiveness. Environmental Health Perspectives 2008;116(11):1500-1508. R832417 (2008)
R832417 (Final)
R832417C003 (2008)
R832417C003 (2009)
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Journal Article Particulate matter disrupts human lung endothelial barrier integrity via ROS- and p38 MAPK-dependent pathways. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY Wang T, Chiang ET, Moreno-Vinasco L, Lang GD, Pendyala S, Samet JM, Geyh AS, Breysse PN, Chillrud SN, Natarajan V, Garcia JGN Wang T, Chiang ET, Moreno-Vinasco L, Lang GD, Pendyala S, Samet JM, Geyh AS, Breysse PN, Chillrud SN, Natarajan V, Garcia JGN. Particulate matter disrupts human lung endothelial barrier integrity via ROS-and p38 MAPK-dependent pathways. American Journal of Respiratory Cell and Molecular Biology 2010;42(4):442-449. R832417 (Final)
R832417C003 (2009)
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Journal Article Hydrogen sulfide attenuates particulate matter-induced human lung endothelial barrier disruption via combined ROS scavenging and Akt activation. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY Wang T, Wang L, Zaidi SR, Sammani S, Siegler J, Moreno-Vinasco L, Mathew B, Natarajan V, Garcia JG Wang T, Wang L, Zaidi SR, Sammani S, Siegler J, Moreno-Vinasco L, Mathew B, Natarajan V, Garcia JG. Hydrogen sulfide attenuates particulate matter-induced human lung endothelial barrier disruption via combined reactive oxygen species scavenging and Akt activation. American Journal of Respiratory Cell and Molecular Biology 2012;47(4):491-496. R832417 (Final)
R832417C003 (Final)
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Journal Article Regulation of COX-2 expression and IL-6 release by particulate matter in airway epithelial cells. None Zhao Y, Usatyuk PV, Gorshkova IA, He D, Wang T, Moreno-Vinasco L, Geyh AS, Breysse PN, Samet JM, Spannhake EW, Garcia JGN, Natarajan V Zhao Y, Usatyuk PV, Gorshkova IA, He D, Wang T, Moreno-Vinasco L, Geyh AS, Breysse PN, Samet JM, Spannhake EW, Garcia JGN, Natarajan V. Regulation of COX-2 expression and IL-6 release by particulate matter in airway epithelial cells. American Journal of Respiratory Cell and Molecular Biology 2009;40(1):19-30. R832417 (2008)
R832417 (Final)
R832417C003 (2008)
R832417C003 (2009)
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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