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Grantee Research Project Results

Journal Publications Details for Grant Number R825268

Pulmonary Toxicity of Particulate Matter and Ozone

RFA: Air Quality (1996)

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Journal Article (5)
Reference Type Reference Title Journal Author Citation Progress Report Year Document Sources
Journal Article Ozone inactivates cyclooxygenase in human tracheal epithelial cells without altering PGHS-2 mRNA or protein. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY Alpert SE, Walenga RW, Jaspers I, Qu QS, Chen LC Alpert SE, Walenga RW, Jaspers I, Qu QS, Chen LC. Ozone inactivates cyclooxygenase in human tracheal epithelial cells without altering PGHS-2 mRNA or protein. American Journal of Physiology-Lung Cellular and Molecular Physiology 1997;16(5):L879-L887. R825268 (Final)
  • Abstract from PubMed
Journal Article A centrifugal particle concentrator for use in inhalation toxicology. INHALATION TOXICOLOGY Gordon T, Gerber H, Fang CP, Chen LC Gordon T, Gerber H, Fang CP, Chen LC. A centrifugal particle concentrator for use in inhalation toxicology. Inhalation Toxicology 1999;11(1):71-87. R825268 (Final)
R826244 (2000)
R826244 (Final)
  • Abstract from PubMed
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Journal Article Ozone-induced IL-8 expression and transcription factor binding in respiratory epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY Jaspers I, Flescher E, Chen LC Jaspers I, Flescher E, Chen LC. Ozone-induced IL-8 expression and transcription factor binding in respiratory epithelial cells. American Journal of Physiology-Lung Cellular and Molecular Physiology 1997;16(3):L504-L511. R825268 (Final)
  • Abstract from PubMed
Journal Article Respiratory epithelial cells display polarity in their release of the chemokine IL-8 after exposure to ozone. INFLAMMATION RESEARCH Jaspers I, Flescher E, Chen LC Jaspers I, Flescher E, Chen LC. Respiratory epithelial cells display polarity in their release of the chemokine IL-8 after exposure to ozone. Inflammation Research 1997;46(Suppl 2):S173-S174. R825268 (Final)
  • Abstract from PubMed
Journal Article Induction of interleukin-8 by ozone is mediated by tyrosine kinase and protein kinase A, but not by protein kinase C. JOURNAL OF CELLULAR PHYSIOLOGY Jaspers I, Chen LC, Flescher E Jaspers I, Chen LC, Flescher E. Induction of interleukin-8 by ozone is mediated by tyrosine kinase and protein kinase A, but not by protein kinase C. Journal of Cellular Physiology 1998;177(2):313-323. R825268 (Final)
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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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