Grantee Research Project Results
Journal Publications Details for Grant Number R827354C003
Clinical Studies of Ultrafine Particle Exposure in Susceptible Human Subjects
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| Reference Type | Reference Title | Journal | Author | Citation | Progress Report Year | Document Sources |
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| Journal Article | Neutrophils in lung inflammation: which reactive oxygen species are being measured? | INHALATION TOXICOLOGY | Azadniv M, Torres A, Boscia J, Speers DM, Frasier LM, Utell MJ, Frampton MW | Azadniv M, Torres A, Boscia J, Speers DM, Frasier LM, Utell MJ, Frampton MW. Neutrophils in lung inflammation: which reactive oxygen species are being measured? Inhalation Toxicology 2001;13(6):485-495. |
R826781 (2001) R826781 (Final) R827354 (2004) R827354 (Final) R827354C003 (2001) R827354C003 (2002) R827354C003 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Journal Article | Comparing inhaled ultrafine versus fine zinc oxide particles in healthy adults: a human inhalation study. | AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | Beckett WS, Chalupa DF, Pauly-Brown A, Speers DM, Stewart JC, Frampton MW, Utell MJ, Huang L-S, Cox C, Zareba W, Oberdorster G | Beckett WS, Chalupa DF, Pauly-Brown A, Speers DM, Stewart JC, Frampton MW, Utell MJ, Huang L-S, Cox C, Zareba W, Oberdorster G. Comparing inhaled ultrafine versus fine zinc oxide particles in healthy adults:a human inhalation study. American Journal of Respiratory and Critical Care Medicine 2005;171(10):1129-1135. |
R827354 (2004) R827354 (Final) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Runs of ventricular and supraventricular tachycardia triggered by air pollution in patients with coronary heart disease. | JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | Berger A, ZarebaW, Schneider A, Ruckerl R, Ibald-Mulli A, Cyrys J, Wichmann HE, Peters A | Berger A, Zareba W, Schneider A, Ruckerl R, Ibald-Mulli A, Cyrys J, Wichmann HE, Peters A. Runs of ventricular and supraventricular tachycardia triggered by air pollution in patients with coronary heart disease. Journal of Occupational and Environmental Medicine 2006;48(11):1149-1158. |
R827354 (Final) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Ultrafine particle deposition in subjects with asthma. | ENVIRONMENTAL HEALTH PERSPECTIVES | Chalupa DC, Morrow PE, Oberdorster G, Utell MJ, Frampton MW | Chalupa DC, Morrow PE, Oberdorster G, Utell MJ, Frampton MW. Ultrafine particle deposition in subjects with asthma. Environmental Health Perspectives 2004;112(8):879-882. |
R827354 (2004) R827354 (Final) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Emission, immission und messung feiner und ultrafeiner partikel (Emission, immission and measurement of fine and ultrafine particles). | UMWELTMEDIZIN FORSCHUNG PRAXIS | Cyrys J, Heinrich J, Peters A, Kreyling W, Wichmann HE | Cyrys J, Heinrich J, Peters A, Kreyling W, Wichmann HE. Emission, immission und messung feiner und ultrafeiner partikel (Emission, immission and measurement of fine and ultrafine particles). Umweltmedizin Forschung Und Praxis 2002;7(2):67-77. |
R827354 (2004) R827354 (Final) R827354C002 (2001) R827354C002 (2002) R827354C002 (Final) R827354C003 (Final) |
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| Journal Article | Ultrafine particle deposition in humans during rest and exercise. | INHALATION TOXICOLOGY | Daigle CC, Chalupa DC, Gibb FR, Morrow PE, Oberdorster G, Utell MJ, Frampton MW | Daigle CC, Chalupa DC, Gibb FR, Morrow PE, Oberdorster G, Utell MJ, Frampton MW. Ultrafine particle deposition in humans during rest and exercise. Inhalation Toxicology 2003;15(6):539-552. |
R826781 (2001) R826781 (Final) R827354 (2004) R827354 (Final) R827354C003 (1999) R827354C003 (2000) R827354C003 (2001) R827354C003 (2002) R827354C003 (2003) R827354C003 (2004) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Systemic interactions between inhaled ultrafine particles and endotoxin. | ANNALS OF OCCUPATIONAL HYGIENE | Elder ACP, Gelein R, Azadniv M, Frampton M, Finkelstein J, Oberdorster G | Elder ACP, Gelein R, Azadniv M, Frampton M, Finkelstein J, Oberdorster G. Systemic interactions between inhaled ultrafine particles and endotoxin. Annals of Occupational Hygiene 2002;46(Suppl 1):231-234. |
R826784 (Final) R827354 (Final) R827354C003 (Final) R827354C004 (Final) R828046 (Final) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Systemic effects of inhaled ultrafine particles in two compromised, aged rat strains. | INHALATION TOXICOLOGY | Elder ACP, Gelein R, Azadniv M, Frampton M, Finkelstein J, Oberdorster G | Elder ACP, Gelein R, Azadniv M, Frampton M, Finkelstein J, Oberdorster G. Systemic effects of inhaled ultrafine particles in two compromised, aged rat strains. Inhalation Toxicology 2004;16(6-7):461-471. |
R826784 (Final) R827354 (Final) R827354C003 (Final) R827354C004 (2003) R827354C004 (Final) R827354C005 (Final) R828046 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) R832415C005 (2011) |
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| Journal Article | Efficient depletion of alveolar macrophages using intratracheally inhaled aerosols of liposome-encapsulated clodronate. | EXPERIMENTAL LUNG RESEARCH | Elder ACP, Gelein R, Oberdorster G, Finkelstein J, Notter R, Wang Z | Elder ACP, Gelein R, Oberdorster G, Finkelstein J, Notter R, Wang Z. Efficient depletion of alveolar macrophages using intratracheally inhaled aerosols of liposome-encapsulated clodronate. Experimental Lung Research 2004;30(2):105-120. |
R827354 (Final) R827354C003 (Final) R827354C004 (2003) R827354C004 (Final) R827354C005 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C004 (2011) R832415C005 (2011) |
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| Journal Article | On-road exposure to highway aerosols. 2. Exposures of aged, compromised rats. | INHALATION TOXICOLOGY | Elder A, Gelein R, Finkelstein J, Phipps R, Frampton M, Utell M, Kittelson DB, Watts WF, Hopke P, Jeong C-H, Kim E, Liu W, Zhao W, Zhuo L, Vincent R, Kumarathasan P, Oberdorster G | Elder A, Gelein R, Finkelstein J, Phipps R, Frampton M, Utell M, Kittelson DB, Watts WF, Hopke P, Jeong C-H, Kim E, Liu W, Zhao W, Zhuo L, Vincent R, Kumarathasan P, Oberdorster G. On-road exposure to highway aerosols. 2. Exposures of aged, compromised rats. Inhalation Toxicology 2004;16(Suppl 1):41-53. |
R827354 (Final) R827354C003 (Final) R827354C004 (2003) R827354C004 (Final) R827354C005 (Final) R828046 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) R832415C005 (2011) |
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| Journal Article | Effects of on-road highway aerosol exposures on autonomic responses in aged, spontaneously hypertensive rats. | INHALATION TOXICOLOGY | Elder A, Couderc J-P, Gelein R, Eberly S, Cox C, Xia X, Zareba W, Hopke P, Watts W, Kittelson D, Frampton M, Utell M, Oberdorster G | Elder A, Couderc J-P, Gelein R, Eberly S, Cox C, Xia X, Zareba W, Hopke P, Watts W, Kittelson D, Frampton M, Utell M, Oberdorster G. Effects of on-road highway aerosol exposures on autonomic responses in aged, spontaneously hypertensive rats. Inhalation Toxicology 2007;19(1):1-12. |
R827354 (Final) R827354C001 (Final) R827354C003 (Final) R827354C004 (Final) R828046 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2006) R832415C004 (2011) |
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| Journal Article | Systemic and cardiovascular effects of airway injury and inflammation: ultrafine particle exposure in humans. | ENVIRONMENTAL HEALTH PERSPECTIVES | Frampton MW | Frampton MW. Systemic and cardiovascular effects of airway injury and inflammation: ultrafine particle exposure in humans. Environmental Health Perspectives 2001;109(Suppl 4):529-532. |
R826781 (2001) R826781 (Final) R827354 (Final) R827354C003 (2001) R827354C003 (2002) R827354C003 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Journal Article | Inhalation of ultrafine particles alters blood leukocyte expression of adhesion molecules in humans. | ENVIRONMENTAL HEALTH PERSPECTIVES | Frampton MW, Stewart JC, Oberdorster G, Morrow PE, Chalupa D, Pietropaoli AP, Frasier LM, Speers DM, Cox C, Huang L-S, Utell MJ | Frampton MW, Stewart JC, Oberdorster G, Morrow PE, Chalupa D, Pietropaoli AP, Frasier LM, Speers DM, Cox C, Huang L-S, Utell MJ. Inhalation of ultrafine particles alters blood leukocyte expression of adhesion molecules in humans. Environmental Health Perspectives 2006;114(1):51-58. |
R826781 (Final) R827354 (Final) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Does inhalation of ultrafine particles cause pulmonary vascular effects in humans? | INHALATION TOXICOLOGY | Frampton MW | Frampton MW. Does inhalation of ultrafine particles cause pulmonary vascular effects in humans? Inhalation Toxicology 2007;19(Suppl 1):75-79. |
R826781 (Final) R827354 (Final) R827354C003 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Journal Article | Characteristics of nucleation and growth events of ultrafine particles measured in Rochester, NY. | ENVIRONMENTAL SCIENCE & TECHNOLOGY | Jeong C-H, Hopke PK, Chalupa D, Utell M | Jeong C-H, Hopke PK, Chalupa D, Utell M. Characteristics of nucleation and growth events of ultrafine particles measured in Rochester, NY. Environmental Science & Technology 2004;38(7):1933-1940. |
R827354 (Final) R827354C001 (2003) R827354C001 (Final) R827354C003 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Journal Article | Influence of atmospheric dispersion and new particle formation events on ambient particle number concentration in Rochester, United States, and Toronto, Canada. | JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION | Jeong C-H, Evans GJ, Hopke PK, Chalupa D, Utell MJ | Jeong C-H, Evans GJ, Hopke PK, Chalupa D, Utell MJ. Influence of atmospheric dispersion and new particle formation events on ambient particle number concentration in Rochester, United States, and Toronto, Canada. Journal of the Air & Waste Management Association 2006;56(4):431-443. |
R827354 (Final) R827354C001 (Final) R827354C003 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Journal Article | Ultrafine particles in the urban air: to the respiratory tract—and beyond? | ENVIRONMENTAL HEALTH PERSPECTIVES | Oberdorster G, Utell MJ | Oberdorster G, Utell MJ. Ultrafine particles in the urban air:to the respiratory tract—and beyond? Environmental Health Perspectives 2002;110(8):A440-A441. |
R826784 (Final) R827354 (Final) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Modeling source contributions to submicron particle number concentrations measured in Rochester, New York. | AEROSOL SCIENCE AND TECHNOLOGY | Ogulei D, Hopke PK, Chalupa DC, Utell MJ | Ogulei D, Hopke PK, Chalupa DC, Utell MJ. Modeling source contributions to submicron particle number concentrations measured in Rochester, New York. Aerosol Science and Technology 2007;41(2):179-201. |
R827354 (Final) R827354C001 (Final) R827354C003 (Final) R831078 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C001 (2011) R832415C003 (2011) |
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| Journal Article | Pulmonary function, diffusing capacity, and inflammation in healthy and asthmatic subjects exposed to ultrafine particles. | INHALATION TOXICOLOGY | Pietropaoli AP, Frampton MW, Hyde RW, Morrow PE, Oberdorster G, Cox C, Speers DM, Frasier LM, Chalupa DC, Huang L-S, Utell MJ | Pietropaoli AP, Frampton MW, Hyde RW, Morrow PE, Oberdorster G, Cox C, Speers DM, Frasier LM, Chalupa DC, Huang L-S, Utell MJ. Pulmonary function, diffusing capacity, and inflammation in healthy and asthmatic subjects exposed to ultrafine particles. Inhalation Toxicology 2004;16(Suppl 1):59-72. |
R826781 (Final) R827354 (Final) R827354C003 (2003) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Ultrafine particle concentrations in a hospital. | INHALATION TOXICOLOGY | Riesenfeld E, Chalupa D, Gibb FR, Oberdo G, Gelein R, Morrow PE, Utell MJ, Frampton MW | Riesenfeld E, Chalupa D, Gibb FR, Oberdo G, Gelein R, Morrow PE, Utell MJ, Frampton MW. Ultrafine particle concentrations in a hospital. Inhalation Toxicology 2000;12(Suppl 2):83-94. |
R826781 (2000) R826781 (2001) R826781 (Final) R827354 (Final) R827354C003 (2000) R827354C003 (2001) R827354C003 (2002) R827354C003 (Final) R827354C004 (2000) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Air pollution and markers of inflammation and coagulation in patients with coronary heart disease. | AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | Ruckerl R, Ibald-Mulli A, Koenig W, Schneider A, Woelke G, Cyrys J, Heinrich J, Marder V, Frampton M, Wichmann HE, Peters A | Ruckerl R, Ibald-Mulli A, Koenig W, Schneider A, Woelke G, Cyrys J, Heinrich J, Marder V, Frampton M, Wichmann HE, Peters A. Air pollution and markers of inflammation and coagulation in patients with coronary heart disease. American Journal of Respiratory and Critical Care Medicine 2006;173(4):432-441. |
R827354 (Final) R827354C002 (2003) R827354C002 (Final) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Journal Article | Real-time characterization of the composition of individual particles emitted from ultrafine particle concentrators. | AEROSOL SCIENCE AND TECHNOLOGY | Su Y, Sipin MF, Spencer MT, Qin X, Moffet RC, Shields LG, Prather KA, Venkatachari P, Jeong C-H, Kim E, Hopke PK, Gelein RM, Utell MJ, Oberdorster G, Berntsen J, Devlin RB, Chen LC | Su Y, Sipin MF, Spencer MT, Qin X, Moffet RC, Shields LG, Prather KA, Venkatachari P, Jeong C-H, Kim E, Hopke PK, Gelein RM, Utell MJ, Oberdorster G, Berntsen J, Devlin RB, Chen LC. Real-time characterization of the composition of individual particles emitted from ultrafine particle concentrators. Aerosol Science and Technology 2006;40(6):437-455. |
R827354 (Final) R827354C001 (Final) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
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| Journal Article | Cardiovascular effects associated with air pollution: potential mechanisms and methods of testing. | INHALATION TOXICOLOGY | Utell MJ, Frampton MW, Zareba W, Devlin RB, Cascio WE | Utell MJ, Frampton MW, Zareba W, Devlin RB, Cascio WE. Cardiovascular effects associated with air pollution:potential mechanisms and methods of testing. Inhalation Toxicology 2002;14(12):1231-1247. |
R826781 (2001) R826781 (Final) R827354 (Final) R827354C003 (2001) R827354C003 (2002) R827354C003 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) |
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| Journal Article | Cardiovascular effects of air pollution: what to measure in ECG? | ENVIRONMENTAL HEALTH PERSPECTIVES | Zareba W, Nomura A, Couderc JP | Zareba W, Nomura A, Couderc JP. Cardiovascular effects of air pollution:what to measure in ECG? Environmental Health Perspectives 2001;109(Suppl 4):533-538. |
R827354 (Final) R827354C003 (Final) R827354C004 (Final) R832415 (2010) R832415 (2011) R832415 (Final) R832415C003 (2011) R832415C004 (2011) |
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.