Fine Particle Sources and Adverse Events in Infants Using Home Cardio-Respiratory Monitors

EPA Grant Number: FP916985
Title: Fine Particle Sources and Adverse Events in Infants Using Home Cardio-Respiratory Monitors
Investigators: Mourning-Star, Phoenix
Institution: Colorado State University
EPA Project Officer: Packard, Benjamin H
Project Period: September 1, 2008 through August 31, 2009
RFA: STAR Graduate Fellowships (2008) RFA Text |  Recipients Lists
Research Category: Academic Fellowships


We will be involved in a project that is studying the relationship between ambient air pollution and cardio-respiratory events (apnea and bradycardia) in a population of primarily preterm and low birth weight infants monitored with home devices. 4,277 infants (aged under six months at the beginning of the study) within the Atlanta metropolitan statistical area were followed by the Apnea Center from August 1, 1998 to December 31, 2002. Patents were prescribed a home monitor for prematurity, gastroesophageal reflux disease, previous apnea events, apparent life threatening events or have a sibling who suffered from Sudden Infant Death Syndrome (SIDS). Cardio-respiratory event data was collected by the Apnea Center of Children’s Healthcare of Atlanta at Egleston. Demographic data, including gender, gestational age, low birth weight, and residential zip code and a unique patient identification number, were also collected.

We will be examining the association between the apnea and bradycardia and source apportioned fine particulate matter from utilization of positive matrix factorization (PMF) and chemical mass balance (CMB) methods. To accomplish this, a number of statistical methods will be utilized. These sources include mobile sources (both gasoline and diesel), biomass burning or wood-smoke, soil, sulfate rich secondary aerosols, and nitrate-risk secondary aerosols.

Expected Results:

It is our expectation through these methods to observe a relationship between sources of air pollutants and the occurrences of adverse cardio-respiratory events which will add to a body of knowledge to further drive policy and regulation.

Supplemental Keywords:

Particulate Matter, PM10, PM2.5, Source Apportionment, positive matrix factorization (PMF), chemical mass balance (CMB),

Progress and Final Reports:

  • Final