Microarray System for Contaminated Water Analysis

EPA Grant Number: R830420C004
Subproject: this is subproject number 004 , established and managed by the Center Director under grant R830420
(EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).

Center: Center for Environmental and Energy Research (CEER)
Center Director: Earl, David A.
Title: Microarray System for Contaminated Water Analysis
Investigators: Cardinale, Jean , DeRosa, Rebecca
Institution: Alfred University
EPA Project Officer: Lasat, Mitch
Project Period: September 1, 2003 through August 31, 2005
RFA: Targeted Research Center (2004) Recipients Lists
Research Category: Hazardous Waste/Remediation , Targeted Research

Objective:

The first objective of this investigation includes developing and optimizing a novel method for glass derivatization followed by antibody adsorption to the glass surface. This will allow us to develop a multiplexed ELISA-on-a-chip system for antigen analysis. The second objective is to adapt our novel ELISA system for pathogen analysis in local recreational waters. The system will have the potential to fulfill a demand for a faster and more cost effective means of testing for multiple pathogens and contaminants in environmental samples.

Publications and Presentations:

Publications have been submitted on this subproject: View all 3 publications for this subprojectView all 34 publications for this center

Journal Articles:

Journal Articles have been submitted on this subproject: View all 1 journal articles for this subprojectView all 6 journal articles for this center

Supplemental Keywords:

ELISA, lab-on-a-chip, water contaminants, glass surface modification, microarray technology, pathogen detection,, RFA, Scientific Discipline, Water, Ecosystem Protection/Environmental Exposure & Risk, Aquatic Ecosystems & Estuarine Research, Environmental Chemistry, Aquatic Ecosystem, Environmental Monitoring, Recreational Water, pathogens, recreational water monitoring, risk assessment, microorganisms, aquatic environments, water quality criteria, microarray system, water quality

Progress and Final Reports:

2004 Progress Report
Final Report


Main Center Abstract and Reports:

R830420    Center for Environmental and Energy Research (CEER)

Subprojects under this Center: (EPA does not fund or establish subprojects; EPA awards and manages the overall grant for this center).
R828737C001 Environmental Impact of Fuel Cell Power Generation Systems
R828737C002 Regional Economic and Material Flows
R828737C003 Visualizing Growth and Sustainability of Water Resources
R828737C004 Vibratory Residual Stress Relief and Modifications in Metals to Conserve Resources and Prevent Pollution
R828737C005 Detecting and Quantifying the Evolution of Hazardous Air Pollutants Produced During High Temperature Manufacturing: A Focus on Batching of Nitrate Containing Glasses
R828737C006 Sulfate and Nitrate Dynamics in the Canacadea Watershed
R828737C007 Variations in Subsurface Denitrifying and Sulfate-Reducing Microbial Populations as a Result of Acid Precipitation
R828737C008 Recycling Glass-Reinforced Thermoset Polymer Composite Materials
R828737C009 Correlating Clay Mineralogy with Performance: Reducing Manufacturing Waste Through Improved Understanding
R830420C001 Accelerated Hydrogen Diffusion Through Glass Microspheres: An Enabling Technology for a Hydrogen Economy
R830420C002 Utilization of Paper Mill Waste in Ceramic Products
R830420C003 Development of Passive Humidity-Control Materials
R830420C004 Microarray System for Contaminated Water Analysis
R830420C005 Material and Environmental Sustainability in Ceramic Processing
R830420C006 Interaction of Sealing Glasses with Metallic Interconnects in Solid Oxide and Polymer Fuel Cells
R830420C007 Preparation of Ceramic Glaze Waste for Recycling using Froth Flotation
R830420C008 Elimination of Lead from Ceramic Glazes by Refractive Index Tailoring
R830420C010 Nanostructured C6B: A Novel Boron Rich Carbon for H2 Storage