Determination of Disinfection By-Products Using Electrospray/Atmospheric Sampling Glow Discharge IonizationEPA Grant Number: U915795
Title: Determination of Disinfection By-Products Using Electrospray/Atmospheric Sampling Glow Discharge Ionization
Investigators: Dalton, Christine N.
Institution: University of North Carolina at Chapel Hill
EPA Project Officer: Packard, Benjamin H
Project Period: December 1, 2000 through December 1, 2002
Project Amount: $61,151
RFA: STAR Graduate Fellowships (2000) RFA Text | Recipients Lists
Research Category: Academic Fellowships , Safer Chemicals , Fellowship - Chemistry and Materials Science
The objective of this research project is to demonstrate that identification and quantitation of polar disinfection by-products in drinking water are possible through a direct approach using electrospray/atmospheric sampling glow discharge ionization with a quadrupole ion trap mass spectrometer.
A direct method will be developed using electrospray/atmospheric sampling glow discharge ionization (ES/ASGDI) coupled to a quadrupole ion trap mass spectrometer. Electrospray is utilized for transporting and nebulizing the sample molecules, while ionization occurs in the atmospheric sampling glow discharge ionization region. Practical instrumental conditions, such as sample pre-concentration, solvent systems, sample size, flow rate, and electrospray voltage along with optimal glow discharge ionization conditions will be investigated to determine the proper method to achieve optimal results. Once instrumental parameters have been optimized to achieve the necessary sensitivity and selectivity, reference spectra will be generated for all of the disinfection by-products of interest. With optimal parameters established, the method detection limit and the linear dynamic range will be determined to ascertain applicability of the method to trace analysis of these disinfection by-products. Once all method parameters have been finalized, applicability of this method to real sample analysis will be investigated by analyzing samples from water treatment facilities across the United States. These samples will be taken throughout the treatment process and analyzed to determine types and quantities of disinfection by-products present in various stages of water treatment.
This method development will serve to circumvent the problems associated with current methodology for disinfection by-products, allowing direct determination of polar disinfection by-products by mass spectrometry.