An Evaluation of the Human Carcinogenic Potential of Ethylene Glycol Butyl Ether (An Interim Position Paper)
In May, 2003, a draft of the position paper received a letter review by five scientists external to EPA. The paper was revised, and the resultant interim final position paper was used as part of the support for the Agency's proposed rule to delist EGBE from the HAP list (68 FR 65648, November 21, 2003). The public comments on this proposed ruling were due January 20, 2004 and can be viewed at www.regulations.gov (ID OAR-2003-0188). The current, interim final position paper states that the existing evidence indicates that prevention of the noncancer effects of EGBE exposure can be expected to prevent carcinogenic outcomes as well. However, it also identified some important genotoxicity and toxicokinetic data gaps that would need to be filled before a definitive determination can be made.
On May 19, 2004, a workshop was held to provide for an external panel review by seven experts capable of evaluating these data gaps and the conclusions of EPA's position paper in light of the recent research and literature that has been submitted to the Agency in response to the Agency's proposed EGBE ruling.
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
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