Health Risk Assessment Approach for 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (Draft)
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Abstract
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is one of the most toxic and environmentally stable pollutants. In addition to various toxic effects, TCDD has been found to cause teratogenic, fetocidal, reproductive and carcinogenic effects in animals. In humans it adversely affects various organ systems and is probably carcinogenic as well. The report documents the methodologies utilized by the United States Environmental Protection Agency in its development of health risk assessment from exposure to TCDD.
Impact/Purpose
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is one of the most toxic and environmentally stable pollutants. In addition to various toxic effects, TCDD has been found to cause teratogenic, fetocidal, reproductive and carcinogenic effects in animals. In humans it adversely affects various organ systems and is probably carcinogenic as well.
Citation
MUKERJEE, D., C. RIS, AND J. SCHAUM. Health Risk Assessment Approach for 2,3,7,8-Tetrachlorodibenzo-P-Dioxin (Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/600/8-85/013 (NTIS PB86-122546/AS), 1985.