IRIS TOXICOLOGICAL REVIEW AND SUMMARY DOCUMENTS FOR XYLENES (EXTERNAL REVIEW DRAFT)
Notice - This site contains archived material(s)
Archived files are provided for reference purposes only. The file was current when produced, but is no longer maintained and may now be outdated. Persons with disabilities having difficulty accessing archived files may contact the NCEA Webmaster for assistance. Please use the contact us form if you need additional support.
The cancer weight of evidence determination for mixed xylenes is group D- not classifiable as to human carcinogenicity by the Guidelines for Carcinogen Risk Assessment (1986) and data are inadequate for an assessment of human carcinogenic potential due to conflicting evidence by the revised draft Guidelines for Carcinogen Risk Assessment (1999).
There is limited information on the relative toxicity of the individual isomers and the results are inconsistent. Based on available data, there do not appear to be susceptible populations.
To access or download the external review draft xylenes document and related IRIS Summary, please refer to the Downloads/URL Links on the left sidebar.
Please direct any correspondence to: Michael Broder, National Center for Environmental Assessment (8601D), U.S. EPA, 1200 Pennsylvania Ave., NW, Washington, DC 20460 or to email@example.com. Also, please send a record keeping copy to: IRIS Submission Desk, c/o ASRC, 6301 Ivy Lane, Suite 300, Greenbelt, MD 20770. Note that this is a new address for the Submission Desk., or email to
This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.