Multiple Classes of Environmental Chemicals Are Associated with Liver Disease: Nhanes 2003-2006 [journal Article]
Biomonitoring of human tissues and fluids has shown that virtually all individuals, worldwide, carry a “body burden” of synthetic chemicals (Thornton et al. 2002; CDC 2009). Although the measurement of an environmental chemical in a person’s tissues or fluids is an indication of exposure, it does not by itself mean that the chemical or the exposure concentration is sufficient to cause a disease or an adverse effect. However, since humans are exposed to multiple chemicals, there may be a combination effect (e.g., additive, synergistic) on health risks associated with exposure even at low levels (Kortenkamp 2008). Further, biomonitoring studies show that humans carry a body burden of multiple classes of contaminants which are often not studied together.
CHRISTENSEN, K. L., C. Carrico, A. Sanyal, AND C. Gennings. Multiple Classes of Environmental Chemicals Are Associated with Liver Disease: Nhanes 2003-2006 [journal Article]. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH. Urban & Fischer Verlag Jena, Jena, Germany, 216(6):703-709, (2013).