IRIS Toxicological Review of Vanadium Pentoxide (Interagency Science Consultation Draft)

Notice - This site contains archived material(s)

Archive disclaimer
Archive disclaimer
Archived files are provided for reference purposes only. These files are no longer maintained by the Agency and may be outdated. For current EPA information, go to www.epa.gov. It is EPA's policy to support reasonable accommodation to persons with disabilities, pursuant to the Rehabilitation Act of 1973, 29 U.S.C. 791. If you need assistance with accessing archived files, contact EPA's Reasonable Accommodations or submit a request using the Contact Us form.


Abstract

On September 30, 2011, the draft Toxicological Review of Vanadium Pentoxide and the charge to external peer reviewers were released for external peer review and public comment. The Toxicological Review and charge were reviewed internally by EPA and by other federal agencies and White House Offices before public release. In the new IRIS process (May 2009), introduced by the EPA Administrator, all written comments on IRIS assessments submitted by other federal agencies and White House Offices will be made publicly available. Accordingly, interagency comments and the interagency science consultation draft of the IRIS Toxicological Review of Vanadium Pentoxide and the charge to external peer reviewers are posted on this site.

Vanadium pentoxide is the most common commercial form of vanadium. It is used as a catalyst in the production of sulfuric acid and some nanomaterials. When fuel oils containing vanadium are combusted, they leave behind byproducts containing vanadium pentoxide in the forms of dust, soot, boiler scale, and fly ash. Vanadium is found at multiple Superfund sites.

Impact/Purpose

EPA is reassessing its IRIS toxicological review of vanadium pentoxide (CASRN 1314-62-1). This vanadium pentoxide reassessment consists of an oral reference dose (RfD), an inhalation reference concentration (RfC), an inhalation unit risk (IUR) and a cancer weight of evidence descriptor. This is the first assessment developing an RfC or IUR for this compound. This assessment is intended to provide human health data to support agency regulatory decisions.

Status

Following external peer review and public comment, the assessment will be revised taking into consideration the comments received. It will then undergo a final internal review by EPA and other federal agencies and White House offices. After completing the review it will be posted to the IRIS database.

Citation

U.S. EPA. IRIS Toxicological Review of Vanadium Pentoxide (Interagency Science Consultation Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-11/004C, 2011.

History/Chronology

Date Description
01-Jan 1987The RfD for vanadium pentoxide was posted to the IRIS Database.
03-Sep 2011EPA hosted an interagency science consultation on the review of the draft Toxicological Review of Vanadium Pentoxide.
04-Sep 2011EPA released the external review draft of the vanadium pentoxide assessment for public review and comment. [Federal Register Notice Sep 30, 2011]

This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.


Related Link(s)