NHEXAS PHASE I MARYLAND STUDY--PESTICIDES IN BLOOD ANALYTICAL RESULTS

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Abstract

The Pesticides in Blood Serum data set contains analytical results for measurements of up to 17 pesticides in 358 blood samples over 79 households. Each sample was collected via a venous sample from the primary respondent within each household by a phlebotomist. Samples were generally drawn on Day #2 but occasionally were drawn on Day #7 of sampling. The samples consist of a 6 ml sample drawn into a 10 mL Vacutainer tube. The primary compounds of interest were persistent organochlorine pesticides represented by a-chlordane (CAS #5103-71-9), g-chlordane (CAS #12789-03-6), 4,4'-DDD (CAS # 72548), 4,4'-DDE (CAS #72559), 4,4'-DDT (CAS #789-02-6), Heptachlor (CAS# 76-44-8), and other compounds. Concentrations in serum as well as lipid-adjusted concentrations are included. Keywords: blood; pesticides.

The National Human Exposure Assessment Survey (NHEXAS) is a federal interagency research effort coordinated by the Environmental Protection Agency (EPA), Office of Research and Development (ORD). Phase I consists of demonstration/scoping studies using probability-based sampling designs. The studies collected household environmental and personal samples for chemical analysis, and questionnaires were administered. The NHEXAS Phase I Questionnaires were organized into six modules for simplicity in administration (to minimize respondent burden and maximize participation rates at each step) and for collecting information that can be temporally related to the exposure, concentration, and/or biological measurements collected in NHEXAS: Descriptive, Baseline, Technician, Follow-up, Time and activity diary, and Dietary diary (and follow-up). The NHEXAS-Maryland study sampled residences determined by a proportion-based sample of Baltimore and four adjacent counties and measured metals, pesticides, and polynuclear aromatic hydrocarbons (PAHs). The study was conducted by Harvard University, Emory University, Johns Hopkins University, and Westat. Data collection occurred up to six times over one year for the participating households. Analytical results were obtained under strict QA/QC requirements during collection, processing, and final deposition into databases.

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