IRIS Toxicological Review of 1,1,2,2-Tetrachloroethane (Interagency Science Discussion Draft)
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Abstract
The draft Toxicological Review of 1,1,2,2-Tetrachloroethane provides scientific support and rationale for the hazard and dose-response assessment pertaining to subchronic and chronic exposure to 1,1,2,2-tetrachloroethane. 1,1,2,2-Tetrachloroethane (1,1,2,2TCE; CASRN 79-34-5) is a synthetic halogenated hydrocarbon that is a colorless, nonflammable liquid at room temperature. The major use for 1,1,2,2-Tetrachloroethane was in the production of trichloroethylene, tetrachloroethylene, and 1,2-Dichloroethylene.
Impact/Purpose
Status
Citation
History/Chronology
Date | Description |
---|---|
Mar 1987 | EPA posted a 1,1,2,2-Tetrachloroethane carcinogenicity assessment. |
Sep 2009 | EPA released an external review draft of the assessment for public review and comment. |
Dec 2009 | EPA announced an external peer review workshop to be held on January 27, 2010 in a December 17, 2009 Federal Register Notice. |
Feb 2010 | EPA released the comments from the external review workshop and the public comment period. |
Aug 2010 | EPA hosted an interagency science discussion on the review of the draft Toxicological Review of 1,1,2,2-tetrachloroethane. |
Sep 2010 | EPA released the final report and the interagency science discussion draft with comments. |
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- Toxicological Review of 1,1,2,2-Tetrachloroethane (Interagency Science Discussion Draft) (PDF) (214 pp, 2 MB, about PDF)
- 1,1,2,2-Tetrachloroethane Summary (Interagency Science Discussion Draft) (PDF) (21 pp, 140 KB, about PDF)
- tetrachloroethane ATSDR IASD Comments (PDF) (1 pp, 48 KB, about PDF)
- tetrachloroethane CEQ IASD Comments (PDF) (1 pp, 40 KB, about PDF)
- tetrachloroethane NIEHS IASD Comments (PDF) (1 pp, 37 KB, about PDF)
- tetrachloroethane OMB IASD Comments (PDF) (3 pp, 26 KB, about PDF)