IRIS Toxicological Review and Summary Documents for Polybrominated Diphenyl Ethers

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EPA has announced the release of four completed toxicologal reviews and summary documents following an independent peer review on the scientific basis supporting the human health hazard and dose-response assessments of four congeners of polybrominated diphenyl ethers: tetraBDE (BDE-47), pentaBDE (BDE-99), hexaBDE (BDE-153), and decaBDE (BDE-209). The final reviews and summary documents are available from the Integrated Risk Information System (IRIS) database.

Please visit the IRIS Web site for specific details: at https://epa.gov/iris


Cover of the Final IRIS Toxicological Review of Hexabromodiphenyl Ether

PBDEs are used as flame retardants in furniture foam, plastics for TV cabinets, consumer electronics, wire insulation, and backcoatings for draperies and upholstery. An assessment of the potential health effects of four individual congeners of polybrominated diphenyl ethers has been completed. These final assessments include reference values for the noncancer effects (RfD and RfC) and a cancer assessment, where supported by available data, for the BDE-47, BDE-99, BDE-153, and BDE-209 congeners of polybrominated diphenyl ethers.