After reports of acute health symptoms (e.g., headache, nausea, eye irritation) arose following the introduction of oxygenated gasoline in Alaska and some other locales in late 1992, EPA, the Centers for Disease Control and Prevention, academic institutions, and other organizations moved quickly to investigate the possible basis for these acute health complaints. Several studies were conducted during the first few months of 1993, including epidemiologic investigations in various communities, experimental inhalation chamber studies of human volunteers and of laboratory animals, personal exposure measurements, and characterizations of vehicle emissions under cold temperature conditions. Results of these and other studies were presented at the "Conference on MTBE and Other Oxygenates: A Research Update," which was held in Falls Church, Virginia, July 26-28, 1993. The Proceedings of the "Conference on MTBE and Other Oxygenates: A Research Update" were issued in 1995.


U.S. EPA. CONFERENCE ON MTBE AND OTHER OXYGENATES. U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, Washington Office, Washington, DC, 1995.

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