IRIS Toxicological Review of Dibutyl Phthalate (DBP) (External Review Draft) 2006
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Dibutyl phthalate is used as a plasticizer for nitrocellulose, polyvinyl acetate, and polyvinyl chloride; a lubricant for aerosol valves; an antifoaming agent; a skin emollient; and a plasticizer in nail polish, fingernail elongators, and hair spray. Dibutyl phthalate is: 1) classified as a Hazardous Air Pollutant under the 1990 Clean Air Act amendments; 2) included on the Office of Prevention, Pesticides and Toxic Substances 1990 high production volume chemical list; 3) listed as a Toxic Release Inventory chemical; and 4) found at hazardous waste and Superfund sites. The assessment will present reference values for the noncancer effects of dibutyl phthalate (RfD and RfC), where supported by available data, and a cancer assessment. The Toxicological Review will be subject to an internal and external peer review.
|Jun 2006||EPA announces an external peer-review workshop to review the external review draft document.|
|Jul 2006||A panel of external peer reviewers met to discuss their responses to the charge questions.|
|Aug 2006||EPA announced the release of the consolidated comments of the external peer reviewers.|
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