INTERSPECIES DIFFERENCES AND HUMAN INTER-INDIVIDUAL VARIABILITY IN TISSUE-LEVEL PHARMACOKINETIC PARAMETERS

Assemble data base of relatively high quality measurements and perform analysis to characterize interspecies extrapolation and inter-individual variability in metabolic parameters for PBPK modeling.

Citation

U.S. EPA. INTERSPECIES DIFFERENCES AND HUMAN INTER-INDIVIDUAL VARIABILITY IN TISSUE-LEVEL PHARMACOKINETIC PARAMETERS.