Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Provisional Peer-Reviewed Toxicity Values for p-α,α,α-Tetrachlorotoluene

EPA announced the release of the final report Provisional Peer-Reviewed Toxicity Values for p-α,α,α-Tetrachlorotoluene (CASRN 5216-25-1). This report support the U.S. EPA's mission to protect human health and the environment by identifying and characterizing the health hazards of chemicals of concern to the Superfund Program, and provide an important source of toxicity information and toxicity values. PPRTVs (provisional oral reference doses [p-RfDs], inhalation reference concentrations [p-RfCs], cancer risk values, and screening values) are derived after a review of the relevant scientific literature and use Agency methodologies, practices, and guidance for developing toxicity values.


U.S. EPA. Provisional Peer-Reviewed Toxicity Values for p-α,α,α-Tetrachlorotoluene. U.S. Environmental Protection Agency, Washington, DC, EPA/690/R-19/002F, 2019.


Sep 2019EPA finalized and delivered the assessment to the Superfund Program. Subchronic and chronic provisional RfDs, subchronic and chronic provisional RfCs, and a provisional oral slope factor were derived and this is the first entry of this chemical into the PPRTV collection.
Nov 2019EPA published the final report and values on the PPRTV website.
Apr 2020EPA released an errata sheet about a formatting update.

This document has been reviewed in accordance with U.S. Environmental Protection Agency policy and approved for publication. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.

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Provisional Peer-Reviewed Toxicity Values (PPRTVs)