Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Lanthanum

CASRN 7439-91-0

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/27/2018
System RfD (mg/kg-day) Basis PoD UF Confidence
Nervous 5 x 10-5 Decreased number of pyramidal cells in hippocampus BMDL : 0.016 mg/kg-day 300
Species Studied: Rat/M
Principal Study: He et al. (2008)


Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/27/2018
System RfD (mg/kg-day) Basis PoD UF Confidence
Nervous 5 x 10-5 Decreased number of pyramidal cells in hippocampus BMDL : 0.016 mg/kg-day 300
Species Studied: Rat/M
Principal Study: He et al. (2008)


Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/27/2018
Not determined

Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/27/2018
Not determined

Cancer Assessment

Weight of Evidence for CancerLast Updated: 09/27/2018
IN - Inadequate Information to Assess Carcinogenic Potential

Estimate of Carcinogenic Risk from Oral ExposureLast Updated: 09/27/2018
Not determined

Estimate of Carcinogenic Risk from Inhalation ExposureLast Updated: 09/27/2018
Not determined

Provisional Peer-Reviewed Toxicity Values (PPRTVs)