Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Thiocyanates

CASRN MULTIPLE

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 03/15/2006
System RfD (mg/kg-day) Basis PoD UF Confidence
Endocrine 2 x 10-4 Changes in thyroid endpoints LOAEL : 0.19 mg/kg-day 1000 Low
Species Studied: Human
Duration: 5 years
Principal Study: Banerjee et al. 1997



Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 03/15/2006
System RfD (mg/kg-day) Basis PoD UF Confidence
Endocrine 6 x 10-4 Changes in thyroid endpoints LOAEL : 0.19 mg/kg-day 300 Low
Species Studied: Human
Duration: 5 years
Principal Study: Banerjee et al. 1997



Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 03/15/2006
Data inadequate for deriving a chronic RfC.


Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 03/15/2006
Data inadequate for deriving a subchronic RfC.

Provisional Peer-Reviewed Toxicity Values (PPRTVs)