Midrange Aliphatic Hydrocarbon Streams
CASRN VARIOUS
PPRTV Toxicity Values Summary Table
Noncancer Assessment
Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/30/2006
See attachment to the assessment's appendix for quantitative screening values.
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/30/2006
See attachment to the assessment's appendix for quantitative screening values.
See attachment to the assessment's appendix for quantitative screening values.
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/30/2006
See attachment to the assessment's appendix for quantitative screening values.
Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/30/2006
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/30/2006
| System | RfC (mg/m3) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Respiratory | 1 x 10-1 | Goblet cell hypertrophy | BMCL : 12 mg/m3 | 100 | Medium |
Species Studied: Rat
Duration: 6 hr/d, 5 d/wk, 14weeks
Principal Study: NTP 2004
Note: The subchronic study was selected as the POD as it is more conservative and a more sensitive indicator of midrange aliphatic hydrocarbon streams exposure
Duration: 6 hr/d, 5 d/wk, 14weeks
Principal Study: NTP 2004
Note: The subchronic study was selected as the POD as it is more conservative and a more sensitive indicator of midrange aliphatic hydrocarbon streams exposure
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/30/2006
| System | RfC (mg/m3) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Respiratory | 1 x 10-1 | Goblet cell hypertrophy | BMCL : 12 mg/m3 | 100 | Medium |
Species Studied: Rat
Duration: 6 hr/d, 5 d/wk, 14weeks
Principal Study: NTP 2004
Note: The subchronic study was selected as the POD as it is more conservative and a more sensitive indicator of midrange aliphatic hydrocarbon streams exposure
Duration: 6 hr/d, 5 d/wk, 14weeks
Principal Study: NTP 2004
Note: The subchronic study was selected as the POD as it is more conservative and a more sensitive indicator of midrange aliphatic hydrocarbon streams exposure
Cancer Assessment
Weight of Evidence for CancerLast Updated: 09/30/2006
SU - Suggestive evidence of carcinogenic potential
Estimate of Carcinogenic Risk from Oral ExposureLast Updated: 09/30/2006
Data are inadequate to derive an oral slope factor.
Estimate of Carcinogenic Risk from Inhalation ExposureLast Updated: 09/30/2006
See attachment to the assessment's appendix for quantitative screening values.
SU - Suggestive evidence of carcinogenic potential
Estimate of Carcinogenic Risk from Oral ExposureLast Updated: 09/30/2006
Data are inadequate to derive an oral slope factor.
Estimate of Carcinogenic Risk from Inhalation ExposureLast Updated: 09/30/2006
See attachment to the assessment's appendix for quantitative screening values.