Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Butyltin Compounds, di-

CASRN VARIOUS

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 03/01/2006
System RfD (mg/kg-day) Basis PoD UF Confidence
Whole Body Effects 3 x 10-4 Immunotoxicity and reduced body weight LOAEL : 0.33 mg/kg-day 1000 Low
Species Studied: Rat
Duration: 9 weeks
Principal Study: Seinen et al. 1977
Note: LOAEL is an average concentration of dibutyltin dichloride.



Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 03/01/2006
System RfD (mg/kg-day) Basis PoD UF Confidence
Whole Body Effects 3 x 10-4 Immunotoxicity and reduced body weight LOAEL : 0.33 mg/kg-day 1000 Low
Species Studied: Rat
Duration: 9 weeks
Principal Study: Seinen et al. 1977
Note: LOAEL is an average concentration of dibutyltin dichloride.



Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 03/01/2006
Data are inadequate to derive a chronic RfC.


Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 03/01/2006
Data are inadequate to derive a subchronic RfC


Cancer Assessment

Weight of Evidence for CancerLast Updated: 03/01/2006
IN - Inadequate information to assess carcinogenic potential

Provisional Peer-Reviewed Toxicity Values (PPRTVs)