Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Vanadium

CASRN 7440-62-2

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/30/2009
System RfD (mg/kg-day) Basis PoD UF Confidence
Urinary 7 x 10-5 Histopathology NOAEL : 0.22 mg/kg-day 3000 Low
Species Studied: Rat
Duration: 6 months
Principal Study: Boscolo et al. 1994
Note: Given exposure to vanadium in the diet, the NOAEL of 0.12 mg/kg-day was adjusted upward by 0.1 mg/kg-day.


Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/30/2009
System RfD (mg/kg-day) Basis PoD UF Confidence
Urinary 7 x 10-4 Histopathology NOAEL : 0.22 mg/kg-day 300 Low
Species Studied: Rat
Duration: 6 months
Principal Study: Boscolo et al. 1994
Note: Given exposure to vanadium in the diet, the NOAEL of 0.12 mg/kg-day was adjusted upward by 0.1 mg/kg-day.


Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/30/2009
Data are inadequate to derive a chronic RfC.

Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/30/2009
Data are inadequate to derive a subchronic RfC.

Cancer Assessment

Weight of Evidence for CancerLast Updated: 09/30/2009
IN - Inadequate information to assess carcinogenic potential.

Provisional Peer-Reviewed Toxicity Values (PPRTVs)