Trinitrophenylmethylnitramine (Tetryl)
CASRN 479-45-8
PPRTV Toxicity Values Summary Table
Noncancer Assessment
Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 08/28/2013
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 08/28/2013
| System | RfD (mg/kg-day) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Hematologic | 2 x 10-3 | Methemoglobinemia | BMDL : 6.1 mg/kg-day | 3000 | Low |
Species Studied: Rat
Duration: 90 days
Principal Study: Reddy et al. 1994b, 1999
Duration: 90 days
Principal Study: Reddy et al. 1994b, 1999
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 08/28/2013
| System | RfD (mg/kg-day) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Hematologic | 2 x 10-2 | Methemoglobinemia | BMDL : 6.1 mg/kg-day | 300 | Low |
Species Studied: Rat
Duration: 90 days
Principal Study: Reddy et al. 1994b, 1999
Duration: 90 days
Principal Study: Reddy et al. 1994b, 1999
Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 08/28/2013
Data are inadequate to derive a chronic or subchronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 08/28/2013
Data are inadequate to derive a subchronic RfC.
Data are inadequate to derive a chronic or subchronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 08/28/2013
Data are inadequate to derive a subchronic RfC.
Cancer Assessment
Weight of Evidence for CancerLast Updated: 08/28/2013
IN - Inadequate for an assessment of carcinogenic potential
IN - Inadequate for an assessment of carcinogenic potential