Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Triethylene Glycol

CASRN 112-27-6

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/10/2014
System RfD (mg/kg-day) Basis PoD UF Confidence
Musculoskeletal 2 Delayed ossification of the supraoccipital bone in fetal mice BMDL05 : 70.8 mg/kg-day 30 High
Species Studied: Mouse
Duration: GD 6-15
Principal Study: Ballantyne and Snellings 2005
Note: The BMDL-05 or 506 mg/kg-day was converted to a HED 0f 70.8 mg/kg-day.


Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/10/2014
System RfD (mg/kg-day) Basis PoD UF Confidence
Musculoskeletal 2 Delayed ossification of the supraoccipital bone in fetal mice BMDL05 : 70.8 mg/kg-day 30 High
Species Studied: Mouse
Duration: GD 6-15
Principal Study: Ballantyne and Snellings 2005
Note: The BMDL-05 or 506 mg/kg-day was converted to a HED 0f 70.8 mg/kg-day.


Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/10/2014
Data are inadequate to derive a chronic RfC.

Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/10/2014
Data are inadequate to derive a subchronic RfC.

Cancer Assessment

Weight of Evidence for CancerLast Updated: 09/10/2014
IN - Inadequate information to assess carcinogenic potential

Provisional Peer-Reviewed Toxicity Values (PPRTVs)