o-Toluidine (Methylaniline, 2-)
CASRN 95-53-4
PPRTV Toxicity Values Summary Table
Noncancer Assessment
Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 12/03/2012
Data are insufficient to derive a chronic RfD.
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 12/03/2012
See attachment to the assessment's appendix for quantitative screening values.
Data are insufficient to derive a chronic RfD.
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 12/03/2012
See attachment to the assessment's appendix for quantitative screening values.
Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 12/03/2012
Data are inadequate to derive a chronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 12/03/2012
Data are inadequate to derive a subchronic RfC.
Data are inadequate to derive a chronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 12/03/2012
Data are inadequate to derive a subchronic RfC.
Cancer Assessment
Weight of Evidence for CancerLast Updated: 12/03/2012
LI - Likely to be carcinogenic to humans
Estimate of Carcinogenic Risk from Oral ExposureLast Updated: 12/03/2012
Oral Slope Factor: 1.6 x 10-2 per mg/kg-day
Tumor site(s):
Cancer: Subcutaneous fibroma and fibrosarcoma
Species Studied: Rat
Duration: 18 months
Principal Study: Wesiburger et al. 1978a
Note:
Estimate of Carcinogenic Risk from Inhalation ExposureLast Updated: 12/03/2012
Data are inadequate to derive an inhalation unit risk.
LI - Likely to be carcinogenic to humans
Estimate of Carcinogenic Risk from Oral ExposureLast Updated: 12/03/2012
Oral Slope Factor: 1.6 x 10-2 per mg/kg-day
Tumor site(s):
Cancer: Subcutaneous fibroma and fibrosarcoma
Species Studied: Rat
Duration: 18 months
Principal Study: Wesiburger et al. 1978a
Note:
Estimate of Carcinogenic Risk from Inhalation ExposureLast Updated: 12/03/2012
Data are inadequate to derive an inhalation unit risk.