Toluene-2,5-diamine dihydrochloride
CASRN 615-45-2
PPRTV Toxicity Values Summary Table
Noncancer Assessment
Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 01/15/2013
See atachment to the assessment appendix for quantitative screening values. The calculated screening RfD of 3E-4 mg/kg-day for Toluene-2,5-diamine sulfate was multiplied by the ratio of molecular weights for 2-Methyl-1,4-benzenediamine dihydrochloride to Toluene-2,5-diamine sulfate to obtain the screening RfD for 2-Methyl-1,4-benzenediamine dihydrochloride.
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 01/15/2013
See attachment to the assessment appendix for quantitative screening values. The calculated screening RfD of 3E-3 mg/kg-day for Toluene-2,5-diamine sulfate was multiplied by the ratio of molecular weights for 2-Methyl-1,4-benzenediamine dihydrochloride to Toluene-2,5-diamine sulfate to obtain the screening RfD for 2-Methyl-1,4-benzenediamine dihydrochloride.
See atachment to the assessment appendix for quantitative screening values. The calculated screening RfD of 3E-4 mg/kg-day for Toluene-2,5-diamine sulfate was multiplied by the ratio of molecular weights for 2-Methyl-1,4-benzenediamine dihydrochloride to Toluene-2,5-diamine sulfate to obtain the screening RfD for 2-Methyl-1,4-benzenediamine dihydrochloride.
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 01/15/2013
See attachment to the assessment appendix for quantitative screening values. The calculated screening RfD of 3E-3 mg/kg-day for Toluene-2,5-diamine sulfate was multiplied by the ratio of molecular weights for 2-Methyl-1,4-benzenediamine dihydrochloride to Toluene-2,5-diamine sulfate to obtain the screening RfD for 2-Methyl-1,4-benzenediamine dihydrochloride.
Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 01/15/2013
Data are inadequate to derive a chronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 01/15/2013
Data are inadequate to derive a subchronic RfC.
Data are inadequate to derive a chronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 01/15/2013
Data are inadequate to derive a subchronic RfC.
Cancer Assessment
Weight of Evidence for CancerLast Updated: 01/15/2013
SU - Suggestive evidence of carcinogenic potential
SU - Suggestive evidence of carcinogenic potential