Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Perylene

CASRN 198-55-0

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 03/24/2023
System RfD (mg/kg-day) Basis PoD UF Confidence
9 x 10-5 Neurobehavioral effects following early postnatal exposure BMDLSD(HED) : 0.092 mg/kg-day 1000
Species Studied: Rat/M,F
Principal Study: Chen et al. (2012); U.S. EPA (2017a)
Note: POD value based on analogue POD


Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 03/24/2023
System RfD (mg/kg-day) Basis PoD UF Confidence
9 x 10-5 Neurobehavioral effects following early postnatal exposure BMDLSD(HED) : 0.092 mg/kg-day 1000
Species Studied: Rat/M,F
Principal Study: Chen et al. (2012); U.S. EPA (2017a)
Note: POD value based on analogue POD


Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 03/24/2023
System RfC (mg/m3) Basis PoD UF Confidence
2 x 10-6 Decreased embryo/fetal survival LOAEL(HEC) : 0.0046 mg/m3 3000
Species Studied: Rat/F
Principal Study: Archibong et al. (2002); U.S. EPA (2017a)
Note: POD value based on analogue POD


Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 03/24/2023
System RfC (mg/m3) Basis PoD UF Confidence
2 x 10-6 Decreased embryo/fetal survival LOAEL(HEC) : 0.0046 mg/m3 3000
Species Studied: Rat/F
Principal Study: Archibong et al. (2002); U.S. EPA (2017a)
Note: POD value based on analogue POD

Cancer Assessment

Weight of Evidence for CancerLast Updated: 03/24/2023
IN - Inadequate information to assess carcinogenic potential

Estimate of Carcinogenic Risk from Oral ExposureLast Updated: 03/24/2023
Not determined

Estimate of Carcinogenic Risk from Inhalation ExposureLast Updated: 03/24/2023
Not determined

Provisional Peer-Reviewed Toxicity Values (PPRTVs)