Perfluorobutane sulfonic acid (PFBS)
CASRN 375-73-5
PPRTV Toxicity Values Summary Table
Noncancer Assessment
Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 04/08/2021
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 04/08/2021
| System | RfD (mg/kg-day) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Endocrine | 3 x 10-4 | Decreased serum total T4 in newborn (PND 1) mice. | BMDL0.5SD : 0.095 mg/kg-day | 300 | Low |
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 04/08/2021
| System | RfD (mg/kg-day) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Endocrine | 1 x 10-3 | Decreased serum total T4 in newborn (PND 1) mice. | BMDL0.5SD : 0.095 mg/kg-day | 100 | Medium |
Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 04/08/2021
Data are inadequate to derive a chronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 04/08/2021
Data are inadequate to derive a subchronic RfC.
Data are inadequate to derive a chronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 04/08/2021
Data are inadequate to derive a subchronic RfC.
Cancer Assessment
Weight of Evidence for CancerLast Updated: 04/08/2021
IN - Inadequate information to assess carcinogenic potential
IN - Inadequate information to assess carcinogenic potential