Provisional Peer-Reviewed Toxicity Values (PPRTVs)

2-Nitroaniline

CASRN 88-74-4

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/11/2009
See attachment to the assessment's appendix for quantitative screening values


Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/11/2009
See attachment to the assessment's appendix for quantitative screening values.



Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/11/2009
See attachment to the assessment's appendix for quantitative screening values.


Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/11/2009
System RfC (mg/m3) Basis PoD UF Confidence
Respiratory ,
Ocular
4 x 10-4 Irritation
Irritation
LOAEL : 0.459 mg/m3 1000 Low/Medium
Species Studied: Rat
Duration: 4 weeks
Principal Study: Bio/Dynamics 1983b
Note: The LOAEL of 9.8 mg/m3 was duration-adjusted and converted to a LOAEL-HEC of 0.459 mg/m3.


Cancer Assessment

Weight of Evidence for CancerLast Updated: 09/11/2009
IN - Inadequate data to assess carcinogenic potential.

Provisional Peer-Reviewed Toxicity Values (PPRTVs)