Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Methylene Bromide

CASRN 74-95-3

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/30/2009
Data are inadequate to derive a chronic RfD.


Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/30/2009
System RfD (mg/kg-day) Basis PoD UF Confidence
Hematologic 9 x 10-3 Reduced serum lactase dehydrogenase NOAEL : 8.6 mg/kg-day 1000 Low
Species Studied: Rat
Duration: 28 days
Principal Study: Komsta et al. 1988



Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/30/2009
See attachment to the assessment's appendix for quantitative screening values.


Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/30/2009
See attachment to the assessment's appendix for quantitative screening values.


Cancer Assessment

Weight of Evidence for CancerLast Updated: 09/30/2009
IN - Inadequate information to assess carcinogenic potential.

Provisional Peer-Reviewed Toxicity Values (PPRTVs)