Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Isobutanol (Isobutyl Alcohol)

CASRN 78-83-1

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 03/24/2023
Please see IRIS.

Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 03/24/2023
Not determined


Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 03/24/2023
System RfC (mg/m3) Basis PoD UF Confidence
Developmental 4 x 10-1 Decreased F2 pup body weights LOAEL : 364.5 mg/m3 1000
Species Studied: Rat/both
Principal Study: Nemec (2003)


Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 03/24/2023
System RfC (mg/m3) Basis PoD UF Confidence
Developmental 1 Decreased F2 pup body weights LOAEL : 364.5 mg/m3 300
Species Studied: Rat/both
Principal Study: Nemec (2003)

Cancer Assessment

Weight of Evidence for CancerLast Updated: 03/24/2023
IN - Inadequate information to assess carcinogenic potential

Estimate of Carcinogenic Risk from Oral ExposureLast Updated: 03/24/2023
Not determined

Estimate of Carcinogenic Risk from Inhalation ExposureLast Updated: 03/24/2023
Not determined

Provisional Peer-Reviewed Toxicity Values (PPRTVs)