Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Hexachlorobenzene

CASRN 118-74-1

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/30/2010
Please see IRIS.


Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/30/2010
System RfD (mg/kg-day) Basis PoD UF Confidence
Endocrine 1 x 10-5 Degenerative changes in primary ovarian follicles LOAEL : 0.01 mg/kg-day 300 Medium
Species Studied: Monkey
Duration: 13 weeks
Principal Study: Bourque et al. 1995



Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/30/2010
Data are inadequate to derive a chronic RfC.


Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/30/2010
Data are inadequate to derive a subchronic RfC.


Cancer Assessment

Weight of Evidence for CancerLast Updated: 09/30/2010
Please see IRIS.

Provisional Peer-Reviewed Toxicity Values (PPRTVs)