4,6-Dinitro-o-cresol
CASRN 534-52-1
PPRTV Toxicity Values Summary Table
Noncancer Assessment
Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 04/22/2010
See attachment to the assessment's appendix for quantitative screening values.
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 04/22/2010
See attachment to the assessment's appendix for quantitative screening values.
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 04/22/2010
| System | RfD (mg/kg-day) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Other , Ocular |
8 x 10-4 | Reduced body weight, excessive perspiration and fatigue, and elevated BMR and body temperature Greenish-yellow coloration of the conjunctivae |
LOAEL : 0.8 mg/kg-day | 1000 | Low |
Species Studied: Human
Duration: Up to 63 days
Principal Study: Ibrahim et al. 1934
Duration: Up to 63 days
Principal Study: Ibrahim et al. 1934
Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 04/22/2010
Data are inadequate to derive a chronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 04/22/2010
Data are inadequate to derive a subchronic RfC.
Data are inadequate to derive a chronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 04/22/2010
Data are inadequate to derive a subchronic RfC.
Cancer Assessment
Weight of Evidence for CancerLast Updated: 04/22/2010
IN - Inadequate information to assess carcinogenic potential
IN - Inadequate information to assess carcinogenic potential