Provisional Peer-Reviewed Toxicity Values (PPRTVs)

trans-Crotonaldehyde

CASRN 123-73-9

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 03/01/2021
System RfD (mg/kg-day) Basis PoD UF Confidence
Gastrointestinal 1 x 10-3 Forestomach hyperplasia BMDL10 : 3 mg/kg-day 3000
Species Studied: Rat/M
Principal Study: Hazleton Laboratories (1986b)



Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 03/01/2021
System RfD (mg/kg-day) Basis PoD UF Confidence
Gastrointestinal 1 x 10-2 Forestomach hyperplasia BMDL10 : 3 mg/kg-day 300
Species Studied: Rat/M
Principal Study: Hazleton Laboratories (1986b)



Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 03/01/2021
Not derived


Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 03/01/2021
Not derived


Cancer Assessment

Weight of Evidence for CancerLast Updated: 07/27/2005
Please see IRIS.

Provisional Peer-Reviewed Toxicity Values (PPRTVs)