2-Chloroethanol
CASRN 107-07-3
PPRTV Toxicity Values Summary Table
Noncancer Assessment
Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 11/26/2012
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 11/26/2012
| System | RfD (mg/kg-day) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Whole Body Effects | 2 x 10-2 | Absence of any toxicological effects and frank effects | NOAEL : 45 mg/kg-day | 300 |
Species Studied: Rat
Duration: 6 weeks, then 12 weeks gavage
Principal Study: Oser et al. 1975a
Duration: 6 weeks, then 12 weeks gavage
Principal Study: Oser et al. 1975a
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 11/26/2012
| System | RfD (mg/kg-day) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Whole Body Effects | 2 x 10-1 | Absence of any toxicological effects and frank effects | NOAEL : 45 mg/kg-day | 300 |
Species Studied: Rat
Duration: 6 weeks, then 12 weeks gavage
Principal Study: Oser et al. 1975a
Duration: 6 weeks, then 12 weeks gavage
Principal Study: Oser et al. 1975a
Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 11/26/2012
Data are inadequate to derive a chronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 11/26/2012
Data are inadequate to derive a subchronic RfC.
Data are inadequate to derive a chronic RfC.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 11/26/2012
Data are inadequate to derive a subchronic RfC.
Cancer Assessment
Weight of Evidence for CancerLast Updated: 11/26/2012
IN - Inadequate for an assessment of carcinogenic potential
IN - Inadequate for an assessment of carcinogenic potential