Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Bromochloromethane

CASRN 74-97-5

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/10/2009
Data are inadequate to derive a chronic RfD.


Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/10/2009
Data are inadequate to derive a subchronic RfD.



Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/10/2009
See attachment to the assessment's appendix for quantitative screening values.


Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/10/2009
System RfC (mg/m3) Basis PoD UF Confidence
Hepatic 1 x 10-1 Increased relative liver weight. LOAEL : 395 mg/m3 3000 Low
Species Studied: Rat
Duration: 7 hr/d, 5 d/wk, for 195 days (135 exposures)
Principal Study: Torkelson et al. 1960
Note: The LOAEL of 1958 mg/m3 was converted to a LOAEL-HEC of 395 mg/m3.


Cancer Assessment

Weight of Evidence for CancerLast Updated: 09/10/2009
IN - Inadequate information to assess carcinogenic potential.

Provisional Peer-Reviewed Toxicity Values (PPRTVs)