Provisional Peer-Reviewed Toxicity Values (PPRTVs)

Benzyl alcohol

CASRN 100-51-6

PPRTV Toxicity Values Summary Table

Noncancer Assessment

Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/30/2009
System RfD (mg/kg-day) Basis PoD UF Confidence
Whole Body Effects 1 x 10-1 Effects on survival, growth, and tissue histopathology NOAEL : 143 mg/kg-day 1000 Low
Species Studied: Mouse
Duration: 5 d/wk, 2 years
Principal Study: NTP 1989a
Note: The NOAEL of 200 mg/kg-day was adjusted for continuous exposure.



Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/30/2009
System RfD (mg/kg-day) Basis PoD UF Confidence
Whole Body Effects 3 x 10-1 Clinical signs of neurotoxicity, such as staggering, labored breathing, and lethargy. NOAEL : 286 mg/kg-day 1000 Low
Species Studied: Mouse
Duration: 5 d/wk, 13 weeks
Principal Study: NTP 1989a
Note: The NOAEL of 400 mg/kg-day was adjusted for continuous exposure.



Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/30/2009
Data are inadequate to derive a chronic RfC.


Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/30/2009
Data are inadequate to derive a subchronic RfC.


Cancer Assessment

Weight of Evidence for CancerLast Updated: 09/30/2009
IN - Inadequate information to assess carcinogenic potential.

Provisional Peer-Reviewed Toxicity Values (PPRTVs)