Allyl Alcohol
CASRN 107-18-6
PPRTV Toxicity Values Summary Table
Noncancer Assessment
Estimate of Chronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/29/2009
Please see IRIS.
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/29/2009
Please see IRIS.
Estimate of Subchronic Reference Dose for Oral Exposure (RfD)Last Updated: 09/29/2009
| System | RfD (mg/kg-day) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Gastrointestinal | 4 x 10-3 | Squamous hyperplasia of the forestomach epithelium | BMDL : 1.3 mg/kg-day | 300 | Medium |
Species Studied: Rat and mouse
Duration: 5 d/wk, 14 weeks
Principal Study: NTP 2006
Duration: 5 d/wk, 14 weeks
Principal Study: NTP 2006
Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/29/2009
See attachment to the assessment's appendix for quantitative screening values.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/29/2009
See attachment to the assessment's appendix for quantitative screening values.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 09/29/2009
| System | RfC (mg/m3) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Whole Body Effects | 1 x 10-3 | No signs of irritation | LOAEL : 1 mg/m3 | 1000 | Low |
Species Studied: Guinea pig
Duration: 6 months
Principal Study: Torkelson et al. 1959
Note: The LOAEL of 4.7 mg/m3 was duration adjusted and converted to a human equivalent concentration.
Duration: 6 months
Principal Study: Torkelson et al. 1959
Note: The LOAEL of 4.7 mg/m3 was duration adjusted and converted to a human equivalent concentration.
Cancer Assessment
Weight of Evidence for CancerLast Updated: 09/29/2009
IN - Inadequate information to assess carcinogenic potential
IN - Inadequate information to assess carcinogenic potential