Adiponitrile
CASRN 111-69-3
PPRTV Toxicity Values Summary Table
Noncancer Assessment
Estimate of Chronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 10/27/2005
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 10/27/2005
| System | RfC (mg/m3) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Hematologic | 6 x 10-3 | Slight anemia without any nonneoplastic lesions | NOAEL : 31 mg/m3 | 1000 | Low/Medium |
Species Studied: Rat
Duration: 13 weeks
Principal Study: Short et al. 1990
Note: NOAEL was converted to a human equivalent concentration, 6 mg/m3.
Duration: 13 weeks
Principal Study: Short et al. 1990
Note: NOAEL was converted to a human equivalent concentration, 6 mg/m3.
Estimate of Subchronic Reference Concentration for Inhalation Exposure (RfC)Last Updated: 10/27/2005
| System | RfC (mg/m3) | Basis | PoD | UF | Confidence |
|---|---|---|---|---|---|
| Hematologic | 6 x 10-2 | Slight anemia without any nonneoplastic lesions | NOAEL : 31 mg/m3 | 100 | Low/Medium |
Species Studied: Rat
Duration: 13 weeks
Principal Study: Short et al. 1990
Note: NOAEL was converted to a human equivalent concentration, 6 mg/m3.
Duration: 13 weeks
Principal Study: Short et al. 1990
Note: NOAEL was converted to a human equivalent concentration, 6 mg/m3.
Cancer Assessment
Weight of Evidence for CancerLast Updated: 10/27/2005
IN - Inadequate information to assess carcinogenic potential
IN - Inadequate information to assess carcinogenic potential