IRIS

This page provides a list of final IRIS assessments with toxicological reviews or support documents in alphabetical order by chemical name.

  Substance Name CASRN IRIS Summary Tox Review/
Support Document
Last Significant Revision*
1 Acetone 67-64-1 IRIS Summary for Acetone (PDF 26 pp, 0.23 M) Toxicological Review for Acetone (PDF 85 pp, 1.19 M) 07/31/2003
2 Acetonitrile 75-05-8 IRIS Summary for Acetonitrile (PDF 23 pp, 165 K) Toxicological Review for Acetonitrile (PDF 35 pp, 144 K) 03/03/1999
3 Acrolein 107-02-8 IRIS Summary for Acrolein (PDF 25 pp, 176 K) Toxicological Review for Acrolein (PDF 106 pp, 332 K) 06/03/2003
4 Acrylamide 79-06-1 IRIS Summary for Acrylamide (PDF 34 pp, 0.32 M) Toxicological Review for Acrylamide (PDF 459 pp, 4.84 M) 03/22/2010
5 Ammonia 7664-41-7 IRIS Summary for Ammonia (PDF 10 pp, 0.31 M) Toxicological Review for Ammonia (PDF 99 pp, 1.00 M)
Ammonia Support Documents
09/20/2016
6 Barium and Compounds 7440-39-3 IRIS Summary for Barium and Compounds (PDF 34 pp, 208 K) Toxicological Review for Barium and Compounds (PDF 88 pp, 325 K) 07/11/2005
7 Bentazon (Basagran) 25057-89-0 IRIS Summary for Bentazon (Basagran) (PDF 20 pp, 145 K) Toxicological Review for Bentazon (Basagran) (PDF 30 pp, 180 K) 03/02/1998
8 Benzene 71-43-2 IRIS Summary for Benzene (PDF 45 pp, 0.26 M) Noncancer Effects Toxicological Review for Benzene (PDF 180 pp, 1.59 M)
Benzene Support Documents
04/17/2003
9 Benzo[a]pyrene (BaP) 50-32-8 IRIS Summary for Benzo[a]pyrene (BaP) (PDF 9 pp, 0.67 M) Toxicological Review for Benzo[a]pyrene (BaP) (PDF 234 pp, 4.67 M)
Benzo[a]pyrene (BaP) Support Documents
01/19/2017
10 Beryllium and compounds 7440-41-7 IRIS Summary for Beryllium and compounds (PDF 51 pp, 284 K) Toxicological Review for Beryllium and compounds (PDF 94 pp, 320 K) 04/03/1998
11 Biphenyl 92-52-4 IRIS Summary for Biphenyl (PDF 12 pp, 0.11 M) Toxicological Review for Biphenyl (PDF 225 pp, 4.82 M) 08/27/2013
12 Boron and Compounds 7440-42-8 IRIS Summary for Boron and Compounds (PDF 30 pp, 193 K) Toxicological Review for Boron and Compounds (PDF 144 pp, 864 K) 08/05/2004
13 Bromate 15541-45-4 IRIS Summary for Bromate (PDF 27 pp, 186 K) Toxicological Review for Bromate (PDF 58 pp, 261 K) 06/06/2001
14 Bromobenzene 108-86-1 IRIS Summary for Bromobenzene (PDF 27 pp, 243 K) Toxicological Review for Bromobenzene (PDF 123 pp, 786 K) 09/30/2009
15 Calcium cyanide 592-01-8 IRIS Summary for Calcium cyanide (PDF 27 pp, 243 K) Toxicological Review for Calcium cyanide (PDF 153 pp, 905 K) 09/28/2010
16 Carbon tetrachloride 56-23-5 IRIS Summary for Carbon tetrachloride (PDF 20 pp, 0.36 M) Toxicological Review for Carbon tetrachloride (PDF 473 pp, 3.04 M) 03/31/2010
17 Cerium Oxide and Cerium Compounds 1306-38-3 IRIS Summary for Cerium Oxide and Cerium Compounds (PDF 19 pp, 205 K) Toxicological Review for Cerium Oxide and Cerium Compounds (PDF 118 pp, 720 K) 09/29/2009
18 Chloral hydrate 302-17-0 IRIS Summary for Chloral hydrate (PDF 39 pp, 220 K) Toxicological Review for Chloral hydrate (PDF 69 pp, 148 K) 09/15/2000
19 Chlordane (Technical) 12789-03-6 IRIS Summary for Chlordane (Technical) (PDF 46 pp, 262 K) Toxicological Review for Chlordane (Technical) (PDF 73 pp, 228 K) 02/07/1998
20 Chlordecone (Kepone) 143-50-0 IRIS Summary for Chlordecone (Kepone) (PDF 24 pp, 0.23 M) Toxicological Review for Chlordecone (Kepone) (PDF 183 pp, 1.03 M) 09/22/2009
21 Chlorine dioxide 10049-04-4 IRIS Summary for Chlorine dioxide (PDF 25 pp, 177 K) Toxicological Review for Chlorine dioxide (PDF 56 pp, 144 K) 10/11/2000
22 Chlorite (sodium salt) 7758-19-2 IRIS Summary for Chlorite (sodium salt) (PDF 19 pp, 143 K) Toxicological Review for Chlorite (sodium salt) (PDF 56 pp, 144 K) 10/11/2000
23 Chloroform 67-66-3 IRIS Summary for Chloroform (PDF 41 pp, 234 K) Toxicological Review for Chloroform (PDF 112 pp, 759 K) 10/19/2001
24 Chloroprene 126-99-8 IRIS Summary for Chloroprene (PDF 30 pp, 0.31 M) Toxicological Review for Chloroprene (PDF 303 pp, 4.63 M)
Chloroprene Support Documents
09/30/2010
25 Chromium(III), insoluble salts 16065-83-1 IRIS Summary for Chromium(III), insoluble salts (PDF 17 pp, 136 K) Toxicological Review for Chromium(III), insoluble salts (PDF 77 pp, 497 K) 09/03/1998
26 Chromium(VI) 18540-29-9 IRIS Summary for Chromium(VI) (PDF 34 pp, 203 K) Toxicological Review for Chromium(VI) (PDF 70 pp, 195 K) 09/03/1998
27 Cumene 98-82-8 IRIS Summary for Cumene (PDF 22 pp, 155 K) Toxicological Review for Cumene (PDF 35 pp, 174 K) 08/01/1997
28 Cyanide, free 57-12-5 IRIS Summary for Cyanide, free (PDF 27 pp, 243 K) Toxicological Review for Cyanide, free (PDF 153 pp, 905 K) 09/28/2010
29 Cyanogen 460-19-5 IRIS Summary for Cyanogen (PDF 27 pp, 243 K) Toxicological Review for Cyanogen (PDF 153 pp, 910 K) 09/28/2010
30 Cyclohexane 110-82-7 IRIS Summary for Cyclohexane (PDF 16 pp, 0.18 M) Toxicological Review for Cyclohexane (PDF 87 pp, 4.80 M) 09/11/2003
31 2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE-209) 1163-19-5 IRIS Summary for 2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE-209) (PDF 25 pp, 232 K) Toxicological Review for 2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether (BDE-209) (PDF 126 pp, 820 K) 06/30/2008
32 1,2-Dibromoethane 106-93-4 IRIS Summary for 1,2-Dibromoethane (PDF 34 pp, 0.24 M) Toxicological Review for 1,2-Dibromoethane (PDF 240 pp, 3.73 M) 07/29/2004
33 Dichloroacetic acid 79-43-6 IRIS Summary for Dichloroacetic acid (PDF 40 pp, 0.32 M) Toxicological Review for Dichloroacetic acid (PDF 192 pp, 1.71 M) 09/11/2003
34 cis-1,2-Dichloroethylene 156-59-2 IRIS Summary for cis-1,2-Dichloroethylene (PDF 16 pp, 0.18 M) Toxicological Review for cis-1,2-Dichloroethylene (PDF 174 pp, 1.18 M) 09/30/2010
35 trans-1,2-Dichloroethylene 156-60-5 IRIS Summary for trans-1,2-Dichloroethylene (PDF 22 pp, 0.22 M) Toxicological Review for trans-1,2-Dichloroethylene (PDF 174 pp, 1.18 M) 09/30/2010
36 1,1-Dichloroethylene (1,1-DCE) 75-35-4 IRIS Summary for 1,1-Dichloroethylene (1,1-DCE) (PDF 37 pp, 225 K) Toxicological Review for 1,1-Dichloroethylene (1,1-DCE) (PDF 72 pp, 531 K) 08/13/2002
37 Dichloromethane 75-09-2 IRIS Summary for Dichloromethane (PDF 44 pp, 0.34 M) Toxicological Review for Dichloromethane (PDF 567 pp, 5.10 M) 11/18/2011
38 1,3-Dichloropropene 542-75-6 IRIS Summary for 1,3-Dichloropropene (PDF 34 pp, 213 K) Toxicological Review for 1,3-Dichloropropene (PDF 83 pp, 394 K) 05/25/2000
39 1,4-Dioxane 123-91-1 IRIS Summary for 1,4-Dioxane (PDF 25 pp, 0.27 M) Toxicological Review for 1,4-Dioxane (PDF 419 pp, 8.52 M) 09/20/2013
40 Ethylene glycol monobutyl ether (EGBE) (2-Butoxyethanol) 111-76-2 IRIS Summary for Ethylene glycol monobutyl ether (EGBE) (2-Butoxyethanol) (PDF 31 pp, 0.30 M) Toxicological Review for Ethylene glycol monobutyl ether (EGBE) (2-Butoxyethanol) (PDF 206 pp, 3.65 M) 03/31/2010
41 Ethylene oxide 75-21-8 IRIS Summary for Ethylene oxide (PDF 9 pp, 0.21 M) Toxicological Review for Ethylene oxide (PDF 228 pp, 1.85 M)
Ethylene oxide Support Documents
12/16/2016
42 2,2',4,4',5,5'-Hexabromodiphenyl ether (BDE-153) 68631-49-2 IRIS Summary for 2,2',4,4',5,5'-Hexabromodiphenyl ether (BDE-153) (PDF 15 pp, 166 K) Toxicological Review for 2,2',4,4',5,5'-Hexabromodiphenyl ether (BDE-153) (PDF 66 pp, 301 K) 06/30/2008
43 Hexachlorocyclopentadiene (HCCPD) 77-47-4 IRIS Summary for Hexachlorocyclopentadiene (HCCPD) (PDF 25 pp, 172 K) Toxicological Review for Hexachlorocyclopentadiene (HCCPD) (PDF 60 pp, 237 K) 07/05/2001
44 Hexachloroethane 67-72-1 IRIS Summary for Hexachloroethane (PDF 34 pp, 0.31 M) Toxicological Review for Hexachloroethane (PDF 200 pp, 1.61 M) 09/23/2011
45 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) 121-82-4 IRIS Summary for Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) (PDF 7 pp, 0.90 M) Toxicological Review for Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) (PDF 187 pp, 2.60 M)
Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) Support Documents
08/30/2018
46 n-Hexane 110-54-3 IRIS Summary for n-Hexane (PDF 28 pp, 0.19 M) Toxicological Review for n-Hexane (PDF 210 pp, 1.40 M) 12/23/2005
47 2-Hexanone 591-78-6 IRIS Summary for 2-Hexanone (PDF 19 pp, 148 K) Toxicological Review for 2-Hexanone (PDF 136 pp, 964 K) 09/25/2009
48 Hydrogen Cyanide and Cyanide Salts Various IRIS Summary for Hydrogen Cyanide and Cyanide Salts (PDF 27 pp, 243 K) Toxicological Review for Hydrogen Cyanide and Cyanide Salts (PDF 153 pp, 905 K) 09/28/2010
49 Hydrogen sulfide 7783-06-4 IRIS Summary for Hydrogen sulfide (PDF 18 pp, 0.14 M) Toxicological Review for Hydrogen sulfide (PDF 74 pp, 1.44 M) 07/28/2003
50 Libby Amphibole asbestos IRIS Summary for Libby Amphibole asbestos (PDF 36 pp, 0.36 M) Toxicological Review for Libby Amphibole asbestos (PDF 685 pp, 8.45 M)
Libby Amphibole asbestos Support Documents
12/08/2014
51 Methanol 67-56-1 IRIS Summary for Methanol (PDF 6 pp, 0.09 M) Toxicological Review for Methanol (PDF 212 pp, 3.46 M) 09/30/2013
52 Methyl chloride 74-87-3 IRIS Summary for Methyl chloride (PDF 23 pp, 165 K) Toxicological Review for Methyl chloride (PDF 95 pp, 337 K) 07/17/2001
53 Methyl ethyl ketone (MEK) 78-93-3 IRIS Summary for Methyl ethyl ketone (MEK) (PDF 33 pp, 211 K) Toxicological Review for Methyl ethyl ketone (MEK) (PDF 152 pp, 570 K) 09/26/2003
54 Methyl isobutyl ketone (MIBK) 108-10-1 IRIS Summary for Methyl isobutyl ketone (MIBK) (PDF 23 pp, 162 K) Toxicological Review for Methyl isobutyl ketone (MIBK) (PDF 68 pp, 547 K) 04/25/2003
55 Methyl methacrylate 80-62-6 IRIS Summary for Methyl methacrylate (PDF 31 pp, 204 K) Toxicological Review for Methyl methacrylate (PDF 83 pp, 275 K) 03/02/1998
56 Methylene Diphenyl Diisocyanate (monomeric MDI) and polymeric MDI (PMDI) 101-68-8 IRIS Summary for Methylene Diphenyl Diisocyanate (monomeric MDI) and polymeric MDI (PMDI) (PDF 23 pp, 170 K) Toxicological Review for Methylene Diphenyl Diisocyanate (monomeric MDI) and polymeric MDI (PMDI) (PDF 54 pp, 154 K) 02/07/1998
57 2-Methylnaphthalene 91-57-6 IRIS Summary for 2-Methylnaphthalene (PDF 21 pp, 158 K) Toxicological Review for 2-Methylnaphthalene (PDF 97 pp, 242 K) 12/22/2003
58 Naphthalene 91-20-3 IRIS Summary for Naphthalene (PDF 32 pp, 102 K) Toxicological Review for Naphthalene (PDF 116 pp, 565 K) 09/17/1998
59 Nitrobenzene 98-95-3 IRIS Summary for Nitrobenzene (PDF 30 pp, 0.26 M) Toxicological Review for Nitrobenzene (PDF 250 pp, 3.83 M) 02/06/2009
60 2,2',4,4',5-Pentabromodiphenyl ether (BDE-99) 60348-60-9 IRIS Summary for 2,2',4,4',5-Pentabromodiphenyl ether (BDE-99) (PDF 20 pp, 0.16 M) Toxicological Review for 2,2',4,4',5-Pentabromodiphenyl ether (BDE-99) (PDF 128 pp, 1.37 M) 06/30/2008
61 Pentachlorophenol 87-86-5 IRIS Summary for Pentachlorophenol (PDF 27 pp, 0.26 M) Toxicological Review for Pentachlorophenol (PDF 288 pp, 2.23 M) 09/30/2010
62 Phenol 108-95-2 IRIS Summary for Phenol (PDF 31 pp, 0.19 M) Toxicological Review for Phenol (PDF 213 pp, 2.96 M) 09/30/2002
63 Phosgene 75-44-5 IRIS Summary for Phosgene (PDF 22 pp, 166 K) Toxicological Review for Phosgene (PDF 102 pp, 614 K) 01/31/2006
64 Potassium cyanide 151-50-8 IRIS Summary for Potassium cyanide (PDF 27 pp, 243 K) Toxicological Review for Potassium cyanide (PDF 153 pp, 910 K) 09/28/2010
65 Potassium silver cyanide 506-61-6 IRIS Summary for Potassium silver cyanide (PDF 27 pp, 243 K) Toxicological Review for Potassium silver cyanide (PDF 153 pp, 910 K) 09/28/2010
66 Propionaldehyde 123-38-6 IRIS Summary for Propionaldehyde (PDF 18 pp, 198 K) Toxicological Review for Propionaldehyde (PDF 78 pp, 559 K) 09/30/2008
67 Quinoline 91-22-5 IRIS Summary for Quinoline (PDF 23 pp, 158 K) Toxicological Review for Quinoline (PDF 40 pp, 163 K) 09/27/2001
68 Sodium cyanide 143-33-9 IRIS Summary for Sodium cyanide (PDF 27 pp, 243 K) Toxicological Review for Sodium cyanide (PDF 153 pp, 905 K) 09/28/2010
69 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) 5436-43-1 IRIS Summary for 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) (PDF 14 pp, 128 K) Toxicological Review for 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) (PDF 85 pp, 380 K) 06/30/2008
70 1,1,2,2-Tetrachloroethane 79-34-5 IRIS Summary for 1,1,2,2-Tetrachloroethane (PDF 29 pp, 250 K) Toxicological Review for 1,1,2,2-Tetrachloroethane (PDF 153 pp, 907 K) 09/30/2010
71 Tetrachloroethylene 127-18-4 IRIS Summary for Tetrachloroethylene (PDF 38 pp, 0.35 M) Toxicological Review for Tetrachloroethylene (PDF 1,077 pp, 144.20 M)
Tetrachloroethylene Support Documents
02/10/2012
72 Tetrahydrofuran 109-99-9 IRIS Summary for Tetrahydrofuran (PDF 26 pp, 0.24 M) Toxicological Review for Tetrahydrofuran (PDF 207 pp, 1.22 M) 02/21/2012
73 Thallium (I), soluble salts Various IRIS Summary for Thallium (I), soluble salts (PDF 17 pp, 0.14 M) Toxicological Review for Thallium (I), soluble salts (PDF 165 pp, 1.00 M) 09/30/2009
74 Thallium acetate 563-68-8 IRIS Summary for Thallium acetate (PDF 17 pp, 0.14 M) Toxicological Review for Thallium acetate (PDF 165 pp, 1.00 M) 09/30/2009
75 Thallium carbonate 6533-73-9 IRIS Summary for Thallium carbonate (PDF 17 pp, 0.14 M) Toxicological Review for Thallium carbonate (PDF 165 pp, 1.00 M) 09/30/2009
76 Thallium chloride 7791-12-0 IRIS Summary for Thallium chloride (PDF 17 pp, 0.14 M) Toxicological Review for Thallium chloride (PDF 165 pp, 1.00 M) 09/30/2009
77 Thallium nitrate 10102-45-1 IRIS Summary for Thallium nitrate (PDF 17 pp, 0.14 M) Toxicological Review for Thallium nitrate (PDF 165 pp, 1.00 M) 09/30/2009
78 Thallium oxide 1314-32-5 IRIS Summary for Thallium oxide (PDF 16 pp, 0.18 M) Toxicological Review for Thallium oxide (PDF 165 pp, 1.00 M) 09/30/2009
79 Thallium selenite 12039-52-0 IRIS Summary for Thallium selenite (PDF 15 pp, 0.13 M) Toxicological Review for Thallium selenite (PDF 165 pp, 1.00 M) 09/30/2009
80 Thallium(I) sulfate 7446-18-6 IRIS Summary for Thallium(I) sulfate (PDF 17 pp, 0.14 M) Toxicological Review for Thallium(I) sulfate (PDF 165 pp, 1.00 M) 09/30/2009
81 Toluene 108-88-3 IRIS Summary for Toluene (PDF 35 pp, 0.23 M) Toxicological Review for Toluene (PDF 179 pp, 1.80 M) 09/23/2005
82 Tributyltin oxide (TBTO) 56-35-9 IRIS Summary for Tributyltin oxide (TBTO) (PDF 33 pp, 205 K) Toxicological Review for Tributyltin oxide (TBTO) (PDF 50 pp, 227 K) 09/01/1997
83 Trichloroacetic acid 76-03-9 IRIS Summary for Trichloroacetic acid (PDF 26 pp, 0.27 M) Toxicological Review for Trichloroacetic acid (PDF 270 pp, 2.08 M) 09/30/2011
84 1,1,1-Trichloroethane 71-55-6 IRIS Summary for 1,1,1-Trichloroethane (PDF 55 pp, 0.39 M) Toxicological Review for 1,1,1-Trichloroethane (PDF 237 pp, 1.08 M) 09/28/2007
85 1,2,3-Trichloropropane 96-18-4 IRIS Summary for 1,2,3-Trichloropropane (PDF 33 pp, 0.28 M) Toxicological Review for 1,2,3-Trichloropropane (PDF 247 pp, 1.91 M) 09/30/2009
86 1,2,3-Trimethylbenzene 526-73-8 IRIS Summary for 1,2,3-Trimethylbenzene (PDF 10 pp, 0.32 M) Toxicological Review for 1,2,3-Trimethylbenzene (PDF 150 pp, 2.65 M)
1,2,3-Trimethylbenzene Support Documents
09/09/2016
87 1,2,4-Trimethylbenzene 95-63-6 IRIS Summary for 1,2,4-Trimethylbenzene (PDF 10 pp, 0.32 M) Toxicological Review for 1,2,4-Trimethylbenzene (PDF 150 pp, 2.65 M)
1,2,4-Trimethylbenzene Support Documents
09/09/2016
88 1,3,5-Trimethylbenzene 108-67-8 IRIS Summary for 1,3,5-Trimethylbenzene (PDF 10 pp, 0.32 M) Toxicological Review for 1,3,5-Trimethylbenzene (PDF 150 pp, 2.65 M)
1,3,5-Trimethylbenzene Support Documents
09/09/2016
89 2,2,4-Trimethylpentane 540-84-1 IRIS Summary for 2,2,4-Trimethylpentane (PDF 12 pp, 170 K) Toxicological Review for 2,2,4-Trimethylpentane (PDF 43 pp, 312 K) 07/31/2007
90 Urea 57-13-6 IRIS Summary for Urea (PDF 14 pp, 125 K) Toxicological Review for Urea (PDF 97 pp, 596 K) 07/13/2011
91 Vinyl chloride 75-01-4 IRIS Summary for Vinyl chloride (PDF 64 pp, 0.34 M) Toxicological Review for Vinyl chloride (PDF 197 pp, 1.20 M) 08/07/2000
92 Xylenes 1330-20-7 IRIS Summary for Xylenes (PDF 33 pp, 203 K) Toxicological Review for Xylenes (PDF 113 pp, 498 K) 02/21/2003
93 Zinc and Compounds 7440-66-6 IRIS Summary for Zinc and Compounds (PDF 21 pp, 154 K) Toxicological Review for Zinc and Compounds (PDF 83 pp, 520 K) 08/03/2005