IRIS

ORD Staff Handbook for Developing IRIS Assessments (Public Comment Draft, Nov 2020)

Notice

EPA is announcing the release of the ORD Staff Handbook for Developing Integrated Risk Information System (IRIS) Assessments, or IRIS Handbook, which EPA has submitted as a notice for publication in the Federal Register (FR). Please refer to the official notice in a forthcoming FR publication, which will appear on the Federal Register website and on Regulations.gov in Docket No. EPA-HQ-ORD-2018-0654.

Overview

The “ORD Staff Handbook for Developing IRIS Assessments,” or “IRIS Handbook,” provides operating procedures for developing assessments to the scientists in the IRIS Program. The IRIS Handbook implements recommendations and input from the National Academy of Sciences, Engineering and Medicine (NASEM), EPA Agency reviewers, other Federal Agencies, EPA’s Science Advisory Board, and workshops involving input from experts in systematic review. The steps in the overall IRIS process have not changed. The IRIS Handbook is designed so that it can be updated, as needed, to allow for incorporation of method refinements, advances in assessment science, and any updates in EPA guidance.

Citation

U.S. EPA. ORD Staff Handbook for Developing IRIS Assessments (Public Comment Draft, Nov 2020). U.S. EPA Office of Research and Development, Washington, DC, EPA/600/R-20/137, 2020.

Contact

Andrew D. Kraft,  Ph:  202-564-0286,  Email: kraft.andrew@epa.gov

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History/Chronology

Date Description
Nov 2020EPA released the draft IRIS Handbook and charge to reviewers for a 90-day public comment period.

Status

EPA is releasing this document and charge questions for public comment in advance of a National Academy of Sciences, Engineering, and Medicine (NASEM) peer review. Following the public comment period, comments received will be summarized and provided to the committee conducting the peer review.


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Download(s)

This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.

Federal Register Notices

Docket

Comments on the assessment may be submitted and reviewed using the Docket ID EPA-HQ-ORD-2018-0654

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