Chromium(VI)
CASRN 18540-29-9
- Toxicological Review (PDF) (70 pp, 195 K)
- IRIS Summary (PDF) (34 pp, 203 K)
- Status: chromium(vi) is in step 5 at this time.
Updated Systematic Review Protocol for the Hexavalent Chromium IRIS Assessment (Preliminary Assessment Materials, 2019)
Notice - This site contains archived material(s).
Archive disclaimer
Archived files are provided for reference purposes only. The file
was current when produced, but is no longer maintained and may now be outdated. Persons with disabilities having difficulty accessing archived
files may contact the Risk Webmaster for assistance. Please use the contact form if you need additional assistance.
Overview
Citation
U.S. EPA. Updated Systematic Review Protocol for the Hexavalent Chromium IRIS Assessment (Preliminary Assessment Materials, 2019). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-18/155, 2019.
Background
This protocol includes strategies for literature searches, criteria for study inclusion or exclusion, considerations for evaluating study methods, information management for extracting data, approaches for synthesis within and across lines of evidence, and methods for derivation of toxicity values.
The IRIS Program posts assessment protocols and protocol updates publicly on a chemical’s HERO project page, the IRIS website, and in systematic review repositories such as Zenodo (https://zenodo.org/record/2654896#.XMsScOhKjcs).
History/Chronology
Date | Description |
---|---|
Apr 2014 | EPA released preliminary meeting materials for chromium (VI), part 1, in preparation for the June 2014 Bimonthly Public Science Meeting. |
Jun 2014 | EPA hosted a public science meeting to discuss preliminary meeting materials for chromium (VI), part 1. |
Aug 2014 | EPA released preliminary meeting materials for chromium (VI), part 2, in preparation for the October 2014 Bimonthly Public Science Meeting. |
Oct 2014 | EPA hosted a public science meeting to discuss preliminary meeting materials for chromium (VI), part 2. |
Mar 2019 | EPA released the Systematic Review Protocol for the Hexavalent Chromium IRIS Assessment (Preliminary Assessment Materials). [Federal Register Notice Mar 15, 2019] |
Apr 2019 | EPA announced that they will host a public science meeting on April 24, 2019 (by webinar) to discuss the draft document. |
Oct 2022 | EPA released an update to the IRIS hexavlent chromium protocol. |
Status
The IRIS Program will use the methods for conducting the systematic review as described in the protocol to develop the draft assessment.
Download(s)
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.
- Systematic Review Protocol for the Hexavalent Chromium IRIS Assessment (Preliminary Assessment Materials) (PDF) (41 pp, 2 MB, about PDF)
- An Update to the Systematic Review Protocol for the Hexavalent Chromium IRIS Assessment (Oct 2022)
- IRIS Public Science Meeting (April 2019) - Hexavalent Chromium
If you have a disability and the format of any material on our web pages interferes with your ability to access the information, please reach out to us using the Contact us about IRIS form for assistance. To enable us to respond in a manner most helpful to you, please indicate the nature of the accessibility problem, the web address of the requested material, your preferred format in which you want to receive the material (electronic format (ASCII, etc.), standard print, large print, etc.), and your contact information.