IRIS

Methanol

CASRN 67-56-1

IRIS Toxicological Review of Methanol (External Review Draft, 2013)

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Overview

EPA is conducting a peer review and public comment of the scientific basis supporting the human health hazard and dose-response assessment of methanol (non-cancer) that when finalized will appear on the Integrated Risk Information System (IRIS) database.

Citation

U.S. EPA. IRIS Toxicological Review of Methanol (External Review Draft, 2013). U.S. Environmental Protection Agency, Washington, DC, 2013.

Contact

Jeffrey S. Gift,  Ph:  919-541-4828,  Email: gift.jeff@epa.gov

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Background

Methanol is a high production volume chemical with many commercial uses. It is a basic building block for numerous chemicals. Many of its derivatives are used in the construction, housing or automotive industries. Consumer products that contain methanol include varnishes, shellacs, paints, windshield washer fluid, antifreeze, adhesives, and deicers. This draft IRIS health assessment addresses non-cancer human health effects that may result from chronic exposure to this chemical. This draft assessment provides an inhalation reference concentration (RfC) for chronic non-cancer health effects and a reassessment of the oral reference dose (RfD).

Additional Information

Comments on the assessment may be submitted and reviewed using the e-Government Regulations.gov Web site. From the site, select “Environmental Protection Agency” and the keyword “EPA-HQ-ORD-2009-0398" (for the docket ID) to comment on this report.

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