- Toxicological Review (PDF) (567 pp, 5.10 M)
- IRIS Summary (PDF) (44 pp, 337 K)
IRIS Toxicological Review of Dichloromethane (Methylene Chloride) (Interagency Science Discussion Draft)
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U.S. EPA. IRIS Toxicological Review of Dichloromethane (Methylene Chloride) (Interagency Science Discussion Draft). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-10/003D, 2011.
The draft Toxicological Review of Dichloromethane provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to dichloromethane. Dichloromethane, also known as methylene chloride, is a colorless liquid. It is, or has been, used principally in paint strippers and removers, as a propellant in aerosols, in the manufacture of drugs, pharmaceuticals, film coatings, electronics, and polyurethane foam, as a metal cleaning solvent, and in the decaffeination process of coffee and tea.
|Dec 2009||EPA hosted an interagency science consultation on the draft Toxicological Review of Dichloromethane.|
|Mar 2010||EPA released the external review draft for public comment. EPA also announced a public listening session on May 11, 2010. [Federal Register Mar 31, 2010]|
|Aug 2010||EPA announced the external peer review meeting to be held on September 23, 2010. [Federal Register Aug 17, 2010]|
|Nov 2010||EPA released the comments from the external review workshop.|
|Aug 2011||EPA hosted an interagency science discussion on the review of the draft Toxicological Review of Dichloromethane.|
|Nov 2011||EPA released the final Toxicological Review and IRIS Summary for Dichloromethane and the interagency review draft with interagency review comments.|
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